外照射放射治疗在肝细胞癌治疗中的作用。
Role of external beam radiation therapy in management of hepatocellular carcinoma.
作者信息
Sharma Hanish
机构信息
Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
出版信息
J Clin Exp Hepatol. 2014 Aug;4(Suppl 3):S122-5. doi: 10.1016/j.jceh.2014.05.002. Epub 2014 Jul 19.
Diagnosis at advanced disease stage and early vascular invasion are the bane of majority of patients with hepatocellular carcinoma (HCC) in India. The currently standardized curative and palliative treatment modalities [surgery, ablative techniques, trans-catheter chemotherapy, systemic chemotherapy] are suboptimal for a significant proportion of disease stages. Interest in radiotherapy for hepatocellular carcinoma has seen a resurgence with revolutionary improvements in targeting radiation doses safely. Encouraging results have been reported with a host of radiation techniques from conformal radiotherapy, stereotactic whole body radiation therapy to charged particle based therapies. The dissemination of this knowledge has been slow across other specialties involved in care of patients with HCC. However the increasing availability of radiotherapy services predicts a hopeful future for wider evaluation of radiotherapy in HCC.
在印度，肝癌患者大多因疾病处于晚期且早期发生血管侵犯而面临困境。目前标准化的根治性和姑息性治疗方式（手术、消融技术、经导管化疗、全身化疗）对于相当一部分疾病阶段而言效果欠佳。随着安全靶向放射剂量方面取得革命性进展，肝癌放疗再度受到关注。从适形放疗、立体定向全身放疗到基于带电粒子的治疗等一系列放射技术均已报告了令人鼓舞的结果。然而，这一知识在参与肝癌患者护理的其他专业领域中的传播较为缓慢。不过，放疗服务的日益普及预示着肝癌放疗有望在更广泛范围内得到评估的光明未来。
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