Ueno Daisuke, Masumoto Kouhei, Sutani Kouichi, Iwaki Sunao
aDepartment of Psychology, Koshien University, Hyogo-Pref bAdvanced Industrial Science and Technology (AIST) Kansai, Osaka cDepartment of Human Development, Kobe University, Kobe dAdvanced Industrial Science and Technology (AIST) Tsukuba Central 6, Ibaraki, Japan.
Neuroreport. 2015 Apr 15;26(6):303-8. doi: 10.1097/WNR.0000000000000325.
This study used magnetoencephalography (MEG) to examine the latency of modality-specific reactivation in the visual and auditory cortices during a recognition task to determine the effects of reactivation on episodic memory retrieval. Nine right-handed healthy young adults participated in the experiment. The experiment consisted of a word-encoding phase and two recognition phases. Three encoding conditions were included: encoding words alone (word-only) and encoding words presented with either related pictures (visual) or related sounds (auditory). The recognition task was conducted in the MEG scanner 15 min after the completion of the encoding phase. After the recognition test, a source-recognition task was given, in which participants were required to choose whether each recognition word was not presented or was presented with which information during the encoding phase. Word recognition in the auditory condition was higher than that in the word-only condition. Confidence-of-recognition scores (d') and the source-recognition test showed superior performance in both the visual and the auditory conditions compared with the word-only condition. An equivalent current dipoles analysis of MEG data indicated that higher equivalent current dipole amplitudes in the right fusiform gyrus occurred during the visual condition and in the superior temporal auditory cortices during the auditory condition, both 450-550 ms after onset of the recognition stimuli. Results suggest that reactivation of visual and auditory brain regions during recognition binds language with modality-specific information and that reactivation enhances confidence in one's recognition performance.
本研究使用脑磁图（MEG）来检测在识别任务期间视觉和听觉皮层中特定模态再激活的潜伏期，以确定再激活对情景记忆检索的影响。九名右利手健康年轻成年人参与了该实验。实验包括一个单词编码阶段和两个识别阶段。包括三种编码条件：单独编码单词（仅单词）以及编码与相关图片（视觉）或相关声音（听觉）一起呈现的单词。识别任务在编码阶段完成15分钟后在MEG扫描仪中进行。在识别测试后，进行了源识别任务，要求参与者选择每个识别单词在编码阶段是否未呈现，或者与哪些信息一起呈现。听觉条件下的单词识别高于仅单词条件下的识别。识别信心分数（d'）和源识别测试表明，与仅单词条件相比，视觉和听觉条件下的表现均更优。对MEG数据进行的等效电流偶极子分析表明，在视觉条件下，右侧梭状回中出现更高的等效电流偶极子振幅，在听觉条件下，颞上听觉皮层中出现更高的等效电流偶极子振幅，均在识别刺激开始后450 - 550毫秒。结果表明，识别过程中视觉和听觉脑区的再激活将语言与特定模态信息结合起来，并且再激活增强了对自身识别表现的信心。
