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葡萄膜炎患者眼内人工晶状体晚期囊袋内脱位

Late in-the-bag intraocular lens dislocation in patients with uveitis.

作者信息

Steeples Laura R, Jones Nicholas P

机构信息

Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

出版信息

Br J Ophthalmol. 2015 Sep;99(9):1206-10. doi: 10.1136/bjophthalmol-2014-306437. Epub 2015 Mar 11.

Abstract

BACKGROUND

Late in-the-bag intraocular lens (IOL) dislocation is an unusual complication of cataract surgery, being strongly associated with pseudoexfoliation, less so with previous vitreoretinal surgery, myopia and uveitis. We present the clinical features, management and outcomes of late spontaneous IOL dislocation in a series of patients with uveitis.

METHODS

A retrospective case series of IOL dislocation affecting patients in the Manchester Uveitis Clinic, UK. The uveitis diagnosis, IOL type, presentation and management are discussed.

RESULTS

Six patients from out of 1056 undergoing cataract surgery (0.57%) were affected. Uveitis was the only identified risk factor for IOL dislocation, which occurred a mean 10.3 years following uncomplicated cataract surgery by phakoemulsification with endocapsular IOL implantation. The dislocation was in-the-bag in all six cases. Two patients presented with the IOL in the anterior chamber, and required removal of the IOL-bag complex, and are using aphakic refractive correction. Two patients with inferior IOL subluxation have been managed conservatively. Two patients underwent pars plana vitrectomy with sutureless scleral fixation of the existing IOL in one case, and IOL exchange with a scleral sutured IOL in the other.

CONCLUSIONS

IOL dislocation is an uncommon late complication in patients with uveitis. Conservative management is appropriate in patients with tolerable symptoms, or in those with difficult uveitis. Otherwise, fixation of the existing IOL, or removal and implantation of a secondary IOL, may be necessary. Angle-supported, or iris-enclaved IOLs, are not of proven safety in this patient group; scleral-fixated posterior chamber IOLs are the favoured approach in our service.

摘要

背景

后房型人工晶状体(IOL)脱位是白内障手术一种罕见的并发症,与假性剥脱密切相关,与既往玻璃体视网膜手术、近视和葡萄膜炎的相关性较小。我们介绍了一系列葡萄膜炎患者中晚期自发性IOL脱位的临床特征、治疗及结果。

方法

对英国曼彻斯特葡萄膜炎诊所受IOL脱位影响的患者进行回顾性病例系列研究。讨论了葡萄膜炎的诊断、IOL类型、表现及治疗。

结果

1056例接受白内障手术的患者中有6例(0.57%)受影响。葡萄膜炎是IOL脱位唯一确定的危险因素,IOL脱位发生在无并发症的白内障超声乳化吸除联合囊内IOL植入术后平均10.3年。所有6例脱位均发生在后房。2例患者前房内见IOL,需取出IOL-囊袋复合体,采用无晶状体屈光矫正。2例IOL向下半脱位患者采用保守治疗。2例患者接受了玻璃体切除术,其中1例对现有IOL进行了无缝线巩膜固定,另1例进行了IOL置换并巩膜缝合IOL。

结论

IOL脱位是葡萄膜炎患者罕见的晚期并发症。对于症状可耐受的患者或葡萄膜炎病情复杂的患者,保守治疗是合适的。否则,可能需要固定现有IOL,或取出并植入二期IOL。在该患者群体中,角支撑或虹膜夹IOL的安全性未经证实;巩膜固定后房型IOL是我们首选的治疗方法。

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