Cots Josep M, Alós Juan-Ignacio, Bárcena Mario, Boleda Xavier, Cañada José L, Gómez Niceto, Mendoza Ana, Vilaseca Isabel, Llor Carles
Centro de Atención Primaria La Marina, Barcelona, España; Sociedad Española de Medicina de Familia y Comunitaria (SemFYC), España.
Servicio de Microbiología, Hospital Universitario de Getafe, Getafe, Madrid, España; Grupo de Estudio de la Infección en Atención Primaria de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (GEIAP-SEIMC), España.
Acta Otorrinolaringol Esp. 2015 May-Jun;66(3):159-70. doi: 10.1016/j.otorri.2015.01.001. Epub 2015 Mar 12.
Acute pharyngitis in adults is one of the most common infectious diseases seen in general practitioners' consultations. Viral aetiology is the most common. Among bacterial causes, the main agent is Streptococcus pyogenes or group A β-haemolytic streptococcus (GABHS), which causes 5%-30% of the episodes. In the diagnostic process, clinical assessment scales can help clinicians to better predict suspected bacterial aetiology by selecting patients who should undergo a rapid antigen detection test. If these techniques are not performed, an overdiagnosis of streptococcal pharyngitis often occurs, resulting in unnecessary prescriptions of antibiotics, most of which are broad spectrum. Consequently, management algorithms that include the use of predictive clinical rules and rapid tests have been set up. The aim of the treatment is speeding up symptom resolution, reducing the contagious time span and preventing local suppurative and non-suppurative complications. Penicillin and amoxicillin are the antibiotics of choice for the treatment of pharyngitis. The association of amoxicillin and clavulanate is not indicated as the initial treatment of acute infection. Neither are macrolides indicated as first-line therapy; they should be reserved for patients allergic to penicillin. The appropriate diagnosis of bacterial pharyngitis and proper use of antibiotics based on the scientific evidence available are crucial. Using management algorithms can be helpful in identifying and screening the cases that do not require antibiotic therapy.
成人急性咽炎是全科医生门诊中最常见的传染病之一。病毒病因最为常见。在细菌病因中,主要病原体是化脓性链球菌或A组β溶血性链球菌(GABHS),其导致5% - 30%的病例。在诊断过程中,临床评估量表可帮助临床医生通过选择应接受快速抗原检测的患者,更好地预测疑似细菌病因。如果不进行这些检测,往往会过度诊断链球菌性咽炎,导致不必要地开具大多数为广谱抗生素的处方。因此,已经建立了包括使用预测性临床规则和快速检测的管理算法。治疗的目的是加速症状缓解、缩短传染期并预防局部化脓性和非化脓性并发症。青霉素和阿莫西林是治疗咽炎的首选抗生素。阿莫西林与克拉维酸的联合用药不作为急性感染的初始治疗。大环内酯类药物也不作为一线治疗药物;它们应保留给对青霉素过敏的患者。基于现有科学证据对细菌性咽炎进行恰当诊断并合理使用抗生素至关重要。使用管理算法有助于识别和筛查不需要抗生素治疗的病例。