N'Goran Alexandra A, Studer Joseph, Deline Stéphane, Henchoz Yves, Baggio Stéphanie, Mohler-Kuo Meichun, Daeppen Jean-Bernard, Gmel Gerhard
a Alcohol Treatment Centre , Lausanne University Hospital (CHUV) , Lausanne , Switzerland.
e Institute for Social Sciences, University of Lausanne , Lausanne , Switzerland.
Subst Abus. 2016;37(1):190-6. doi: 10.1080/08897077.2015.1013204. Epub 2015 Mar 16.
Obesity and substance use are major concern in young people. This study explored the bidirectional longitudinal relationships between the body mass index (BMI) of young men and their use of (1) 4 classes of nonmedical prescription drugs; (2) alcohol; (3) tobacco; and (4) cannabis.
Baseline and follow-up data from the Cohort Study on Substance Use Risk Factors were used (N = 5007). A cross-lagged panel model, complemented by probit models as sensitivity analysis, was run to determine the bidirectional relationships between BMI and substance use. Alcohol was assessed using risky single-occasion drinking (RSOD); tobacco, using daily smoking; and cannabis, using hazardous cannabis use (defined as twice-weekly or more cannabis use). Nonmedical prescription drugs use (NMPDU) included opioid analgesics, sedatives/sleeping pills, anxiolytics, and stimulants.
Different associations were found between BMI and substance use. Only RSOD (β = -.053, P = .005) and NMPDU of anxiolytics (β = .040, P = .020) at baseline significantly predicted BMI at follow-up. Baseline RSOD predicted a lower BMI at follow-up, whereas baseline NMPDU of anxiolytics predicted higher BMI at follow-up. Furthermore, BMI at baseline significantly predicted daily smoking (β = .050, P = .007) and hazardous cannabis use (β = .058, P = .030).
These results suggest different associations between BMI and the use of various substances by young men. However, only RSOD and NMPDU of anxiolytics predicted BMI, whereas BMI predicted daily smoking and hazardous cannabis use.
肥胖和物质使用是年轻人中的主要问题。本研究探讨了年轻男性体重指数(BMI)与他们使用(1)四类非医疗处方药;(2)酒精;(3)烟草;以及(4)大麻之间的双向纵向关系。
使用了物质使用风险因素队列研究的基线和随访数据(N = 5007)。运行交叉滞后面板模型,并辅以概率模型作为敏感性分析,以确定BMI与物质使用之间的双向关系。酒精使用风险单次饮酒(RSOD)进行评估;烟草使用每日吸烟情况评估;大麻使用危险大麻使用情况(定义为每周两次或更多次使用大麻)评估。非医疗处方药使用(NMPDU)包括阿片类镇痛药、镇静剂/安眠药、抗焦虑药和兴奋剂。
BMI与物质使用之间发现了不同的关联。仅基线时的RSOD(β = -.053,P = .005)和抗焦虑药的NMPDU(β = .040,P = .020)显著预测了随访时的BMI。基线RSOD预测随访时BMI较低,而基线抗焦虑药的NMPDU预测随访时BMI较高。此外,基线时的BMI显著预测了每日吸烟(β = .050,P = .007)和危险大麻使用(β = .058,P = .030)。
这些结果表明年轻男性的BMI与各种物质使用之间存在不同的关联。然而,只有RSOD和抗焦虑药的NMPDU预测了BMI,而BMI预测了每日吸烟和危险大麻使用。