Kash Natalie, Jahan-Tigh Richard Reza, Efron-Everett Melissa, Vigneswaran Nadarajah
The Department of Dermatology The University of Texas Medical School at Houston and MD Anderson Cancer Center Houston, Texas.
Dermatol Online J. 2014 Dec 14;21(3):13030/qt87614080.
We report a case of primary mucocutaneous histoplasmosis in an immunocompetent individual. The patient, a 61-year-old woman, presented with a non-healing ulcer on the lateral border of her tongue. Excisional biopsy of the lesion was consistent with histoplasmosis and no evidence of pulmonary or disseminated infection was found. Although mucocutaneous infection has been well-described as a manifestation of disseminated disease, especially in immunocompromised individuals, oral infections in immunocompetent patients are rare.
我们报告一例免疫功能正常个体的原发性皮肤黏膜组织胞浆菌病病例。患者为一名61岁女性,舌外侧缘有一不愈合溃疡。病变切除活检结果符合组织胞浆菌病,未发现肺部或播散性感染的证据。虽然皮肤黏膜感染已被充分描述为播散性疾病的一种表现,尤其是在免疫功能低下的个体中,但免疫功能正常患者的口腔感染较为罕见。