Berman Loren, Sharif Iman, Rothstein David, Hossain Jobayer, Vinocur Charles
Nemours-A.I. duPont Hospital for Children, Wilmington, DE.
Nemours-A.I. duPont Hospital for Children, Wilmington, DE.
J Pediatr Surg. 2015 Jul;50(7):1104-8. doi: 10.1016/j.jpedsurg.2014.07.013. Epub 2014 Oct 1.
Fundoplication is often performed in conjunction with gastrostomy tube (GT) placement in children, but there is a great deal of variation in rates of and indications for this procedure. Little is known about the impact of fundoplication on peri-operative outcomes. This study examines a national cohort of pediatric patients to compare risk-adjusted surgical outcomes in patients undergoing GT placement with or without concomitant fundoplication.
We identified all patients undergoing GT placement in the 2012 National Surgical Quality Improvement Program - Pediatric. We evaluated demographics, comorbidities, complications, and length of stay for GT with fundoplication versus GT alone. We defined composite morbidity as a dichotomous variable for the presence of any complication. Logistic regression was performed to identify predictors of morbidity after adjusting for covariates.
1289 GT patients were identified, and 148 (11.5%) underwent concurrent fundoplication. The fundoplication patients were more likely to be younger, have cardiac risk factors, and be on respiratory support. They also had higher rates of surgical site infection (7.4% vs 3.7%, p=0.03) and composite morbidity (16.9% vs 8.7%, p=0.001), and longer LOS (median 5 vs 3 days, p=<0.0001) compared to GT only. After adjusting for covariates, fundoplication was a predictor of composite morbidity and increased LOS.
Concomitant fundoplication is an independent risk factor for 30-day post-operative morbidity in patients undergoing GT placement. These findings do not negate the value of fundoplication but underscore the importance of careful patient selection, and should be taken into consideration when discussing risks and benefits with families.
胃底折叠术常在儿童胃造口管(GT)置入时同时进行,但该手术的发生率和适应症存在很大差异。关于胃底折叠术对围手术期结局的影响知之甚少。本研究调查了一组全国性的儿科患者,以比较接受或未接受同期胃底折叠术的GT置入患者经风险调整后的手术结局。
我们在2012年国家外科质量改进计划 - 儿科中确定了所有接受GT置入的患者。我们评估了人口统计学、合并症、并发症以及接受胃底折叠术联合GT与单纯GT治疗患者的住院时间。我们将复合发病率定义为存在任何并发症的二分变量。在对协变量进行调整后,进行逻辑回归以确定发病的预测因素。
共确定了1289例GT患者,其中148例(11.5%)同时接受了胃底折叠术。接受胃底折叠术的患者更可能年龄较小、有心脏危险因素且接受呼吸支持。与单纯GT相比,他们的手术部位感染率(7.4%对3.7%,p = 0.03)和复合发病率(16.9%对8.7%,p = 0.001)更高,住院时间更长(中位数5天对3天,p < 0.0001)。在对协变量进行调整后,胃底折叠术是复合发病率和住院时间延长的预测因素。
同期胃底折叠术是接受GT置入患者术后30天发病的独立危险因素。这些发现并不否定胃底折叠术的价值,但强调了谨慎选择患者的重要性,并且在与家属讨论风险和益处时应予以考虑。