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与拖出式手术相比,后矢状位肛门直肠成形术在成年后可带来更好的肠道功能和生活质量。

Posterior sagittal anorectoplasty results in better bowel function and quality of life in adulthood than pull-through procedures.

作者信息

Danielson Johan, Karlbom Urban, Graf Wilhelm, Olsen Leif, Wester Tomas

机构信息

Institution of Surgical sciences, Uppsala University, Uppsala, Sweden; Institution of Women's and Children's Health, Uppsala University, Uppsala, Sweden; Department of Pediatric Surgery, Akademiska Sjukhuset, Uppsala, Sweden.

Institution of Surgical sciences, Uppsala University, Uppsala, Sweden; Department of Surgery, Akademiska Sjukhuset, Uppsala, Sweden.

出版信息

J Pediatr Surg. 2015 Sep;50(9):1556-9. doi: 10.1016/j.jpedsurg.2015.02.004. Epub 2015 Feb 14.

Abstract

BACKGROUND/PURPOSE: The short-term outcome of posterior sagittal anorectoplasty (PSARP) procedure has been reported to be better than after abdominoperineal or abdominosacroperineal (AP) procedures. This study aimed to investigate the long-term functional outcome and quality of life after PSARP in adulthood and compare with the outcome after AP procedures.

METHODS

Twenty-four patients operated with PSARP at the Department of Pediatric Surgery, Uppsala, Sweden, from 1984 to 1993 were identified. They were compared with 20 patients that underwent AP pull-through procedures from 1974 to 1983. The patients were sent validated bowel function and quality of life (SF-36) questionnaires. Sixteen PSARP (median age 21, five females) patients and fourteen AP patients (seven abdominosacroperineal and seven abdominoperineal pull-throughs, median age 32, seven females) responded and were included in the study.

RESULTS

The median Miller incontinence score was 1 (range 0-13) in the PSARP group and 10 (range 3-16) in the pull-through group (P=0.0042). The use of underwear protection and oral loperamide was significantly less frequent in the PSARP group (P=0.0096 and 0.0021 respectively). The SF-36 scores of Vitality, Mental health and Mental Cluster Scale were higher in the PSARP group (P=0.0291, 0.0500, 0.0421 respectively).

CONCLUSIONS

PSARP results in superior bowel function and better quality of life in adulthood compared with AP procedures for the repair of anorectal malformations.

摘要

背景/目的:据报道,后矢状位肛门直肠成形术(PSARP)的短期疗效优于腹会阴或腹骶会阴(AP)手术。本研究旨在调查成年后PSARP的长期功能结局和生活质量,并与AP手术的结局进行比较。

方法

确定了1984年至1993年在瑞典乌普萨拉小儿外科接受PSARP手术的24例患者。将他们与1974年至1983年接受AP拖出术的20例患者进行比较。向患者发送了经过验证的肠道功能和生活质量(SF-36)问卷。16例PSARP患者(中位年龄21岁,5名女性)和14例AP患者(7例腹骶会阴和7例腹会阴拖出术,中位年龄32岁,7名女性)做出了回应并纳入研究。

结果

PSARP组的米勒失禁评分中位数为1(范围0-13),拖出术组为10(范围3-16)(P=0.0042)。PSARP组使用内衣保护和口服洛哌丁胺的频率明显较低(分别为P=0.0096和0.0021)。PSARP组的SF-36活力、心理健康和心理综合量表评分更高(分别为P=0.0291、0.0500、0.0421)。

结论

与AP手术修复肛门直肠畸形相比,PSARP在成年后可带来更好的肠道功能和生活质量。

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