针对人源和嵌合抗 TNF 治疗性抗体的抗体反应主要靶向 TNF 结合区域。 - Suppr

The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

作者信息

Rinaudo-Gaujous M, Roblin X, Marotte H, Paul S

机构信息

Laboratoire d'Immunologie et d'immunomonitoring, CIC INSERM 1408, GIMAP EA3064, CHU de Saint-Etienne, Saint-Etienne, France.

Service de Gastro-Entérologie-Hépatologie, CHU de Saint-Etienne, Saint-Etienne, France.

出版信息

Ann Rheum Dis. 2015 Aug;74(8):e40. doi: 10.1136/annrheumdis-2015-207503. Epub 2015 Mar 23.

DOI:10.1136/annrheumdis-2015-207503

PMID:25802246

Abstract

摘要

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The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

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The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

作者信息

Rinaudo-Gaujous M, Roblin X, Marotte H, Paul S

机构信息

Laboratoire d'Immunologie et d'immunomonitoring, CIC INSERM 1408, GIMAP EA3064, CHU de Saint-Etienne, Saint-Etienne, France.

Service de Gastro-Entérologie-Hépatologie, CHU de Saint-Etienne, Saint-Etienne, France.

出版信息

Ann Rheum Dis. 2015 Aug;74(8):e40. doi: 10.1136/annrheumdis-2015-207503. Epub 2015 Mar 23.

DOI:10.1136/annrheumdis-2015-207503

PMID:25802246

Abstract

摘要

相似文献

The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

Ann Rheum Dis. 2015 Aug;74(8):e40. doi: 10.1136/annrheumdis-2015-207503. Epub 2015 Mar 23.

Response to: 'The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region' by Rinaudo-Gaujous et al.

Ann Rheum Dis. 2015 Aug;74(8):e41. doi: 10.1136/annrheumdis-2015-207529. Epub 2015 Apr 8.

The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

Ann Rheum Dis. 2015 Jan;74(1):311-4. doi: 10.1136/annrheumdis-2014-206237. Epub 2014 Oct 23.

Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.

Ann Rheum Dis. 2013 Jan;72(1):104-9. doi: 10.1136/annrheumdis-2012-201445. Epub 2012 Jul 3.

Prevalence of TNF-α blocker immunogenicity in psoriatic arthritis.

J Rheumatol. 2015 Jan;42(1):73-8. doi: 10.3899/jrheum.140685. Epub 2014 Nov 15.

The effect of certolizumab drug concentration and anti-drug antibodies on TNF neutralisation.

Clin Exp Rheumatol. 2020 Mar-Apr;38(2):306-313. doi: 10.55563/clinexprheumatol/nlr4r8. Epub 2019 Aug 30.

Clinical Efficacy and Safety of Ixekizumab for Treatment of Psoriasis.

Actas Dermosifiliogr. 2017 May;108(4):305-314. doi: 10.1016/j.ad.2016.09.021. Epub 2016 Nov 22.

Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation.

Ann Rheum Dis. 2013 Oct;72(10):1680-6. doi: 10.1136/annrheumdis-2012-202407. Epub 2013 Jan 7.

Thromboembolic events and anti-tumor necrosis factor therapies.

Int Immunopharmacol. 2012 Dec;14(4):444-5. doi: 10.1016/j.intimp.2012.08.018. Epub 2012 Sep 3.

Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.

J Biol Chem. 2014 Dec 12;289(50):34482-8. doi: 10.1074/jbc.M114.615500. Epub 2014 Oct 17.

引用本文的文献

Int J Mol Sci. 2022 Mar 22;23(7):3426. doi: 10.3390/ijms23073426.

Methotrexate Reduced TNF Bioactivity in Rheumatoid Arthritis Patients Treated with Infliximab.

Mediators Inflamm. 2017;2017:3708250. doi: 10.1155/2017/3708250. Epub 2017 Mar 2.

The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

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The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

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