Fine Ronnie, Reda Edward F, Zelkovic Paul, Gitlin Jordan, Freyle Jaime, Franco Israel, Palmer Lane S
Cohen Children's Medical Center, Hofstra North Shore-LIJ School of Medicine, Flushing, New York.
Cohen Children's Medical Center, Hofstra North Shore-LIJ School of Medicine, Flushing, New York.
J Urol. 2015 May;193(5 Suppl):1813-7. doi: 10.1016/j.juro.2014.10.093. Epub 2015 Mar 25.
Buccal mucosa is the favored graft material for patients with long urethral defects and a paucity of skin. Since 2007, we have used the novel tunneled buccal mucosa tube graft urethroplasty technique in these patients. We describe this operative technique and report our surgical and functional outcomes.
Between 2007 and 2013, 37 males with proximal hypospadias underwent tunneled buccal mucosa tube graft urethroplasty. After the penile shaft was optimized at a prior stage a free buccal graft was tubularized and tunneled under the intact ventral shaft skin and into the glans. We retrospectively reviewed all charts to report our results. We assessed uroflowmetry and bladder ultrasound for post-void residual urine.
The overall complications rate in 34 patients with more than 1-year followup was 32% (11), including fistula in 5, proximal stricture in 4 and meatal stenosis in 2. In the first 10 patients a total of 7 complications (70%) developed but there were only 4 complications in the next 24 (16%). Surgeon experience was the only significant predictor of complications (p = 0.003). We obtained uroflow and post-void residual urine data on 13 of 37 patients, of whom 9 achieved a normal flow pattern and post-void residual urine, and 4 had a blunted flow pattern.
The novel technique of the tunneled buccal mucosa tube graft in patients with proximal hypospadias represents a good alternative for a long urethroplasty in patients with a paucity of skin. After the learning curve plateaus the rate and degree of complications decrease. Furthermore, voiding function is adequate, as assessed by uroflow studies and post-void residual urine measurement.
对于尿道缺损长且皮肤匮乏的患者,颊黏膜是首选的移植材料。自2007年以来,我们在这些患者中采用了新型带隧道颊黏膜管移植尿道成形术。我们描述了这种手术技术并报告了我们的手术和功能结果。
2007年至2013年期间,37例近端型尿道下裂男性患者接受了带隧道颊黏膜管移植尿道成形术。在阴茎干先前已优化后,将游离颊黏膜移植片制成管状,并在完整的腹侧阴茎干皮肤下带隧道进入龟头。我们回顾性查阅了所有病历以报告我们的结果。我们评估了尿流率以及膀胱超声检查以测定排尿后残余尿量。
在34例随访超过1年的患者中,总体并发症发生率为32%(11例),包括瘘管形成5例、近端狭窄4例和尿道口狭窄2例。在前10例患者中,共发生7例并发症(70%),但在接下来的24例患者中仅发生4例并发症(16%)。外科医生的经验是并发症的唯一显著预测因素(p = 0.003)。我们获取了37例患者中13例的尿流率和排尿后残余尿量数据,其中9例尿流模式和排尿后残余尿量正常,4例尿流模式减弱。
近端型尿道下裂患者采用的新型带隧道颊黏膜管移植技术,对于皮肤匮乏的患者进行长段尿道成形术是一种很好的替代方法。在学习曲线趋于平稳后,并发症的发生率和严重程度会降低。此外,通过尿流研究和排尿后残余尿量测量评估,排尿功能良好。