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带蒂鼻中隔瓣在岩尖胆固醇肉芽肿内镜治疗中的应用。

Use of the pedicled nasoseptal flap in the endoscopic management of cholesterol granulomas of the petrous apex.

作者信息

Karligkiotis Apostolos, Bignami Maurizio, Terranova Paola, Ciniglio-Appiani Mario, Shawkat Abdulrahman, Verrilaud Benjamin, Meloni Francesco, Herman Philippe, Castelnuovo Paolo

机构信息

Division of Otorhinolaryngology, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

出版信息

Int Forum Allergy Rhinol. 2015 Aug;5(8):747-53. doi: 10.1002/alr.21521. Epub 2015 Mar 26.

Abstract

BACKGROUND

Nowadays the endoscopic approach represents a useful alternative to traditional surgical approaches in the treatment of cholesterol granulomas (CGs) of the petrous apex (PA). Recently the nasoseptal flap (NSF) has been employed to permit long-term patency of drainage site. The purpose of this study is to report our experience with the NSF in the endoscopic management of CG and to analyze the advantages, limitations, and outcomes of the technique.

METHODS

A retrospective analysis was carried out on 10 patients affected by CG of the PA who had been treated endoscopically, using the NSF.

RESULTS

An endoscopic transpterygoid approach was used for 6 patients and the remaining 4 were treated using the transclival approach. A NSF was used in all 10 cases. In 6 cases the flap was ipsilateral to the lesion whereas in 4 it was contralateral. In 90% of our patients no evidence of disease was observed after a mean follow-up period of 35.7 months, with resolution of their symptoms. One patient presented a recurrence because of a technical error (inadequate placement of the flap in the cavity), and has been retreated endoscopically.

CONCLUSION

The pedicled NSF seems to be helpful in avoiding the concentric growth of the granulomatous cyst epithelium while assuring ventilation and drainage of the cyst. However, bigger studies with longer-term follow-up are needed to confirm these findings. Correct and meticulous placement of the flap inside the cystic cavity is the most critical issue for the success of the procedure.

摘要

背景

如今,在内镜治疗岩尖胆固醇肉芽肿(CG)方面,内镜方法是传统手术方法的一种有效替代方案。最近,鼻中隔瓣(NSF)已被用于确保引流部位的长期通畅。本研究的目的是报告我们在内镜治疗CG中使用NSF的经验,并分析该技术的优点、局限性和结果。

方法

对10例接受内镜下NSF治疗的岩尖CG患者进行回顾性分析。

结果

6例患者采用内镜经翼突入路,其余4例采用经斜坡入路。所有10例均使用了NSF。6例中瓣位于病变同侧,4例位于对侧。平均随访35.7个月后,90%的患者症状消失,未发现疾病迹象。1例患者因技术失误(瓣在腔内放置不当)复发,已接受内镜再次治疗。

结论

带蒂NSF似乎有助于避免肉芽肿性囊肿上皮的同心生长,同时确保囊肿的通气和引流。然而,需要更大规模、更长时间随访的研究来证实这些发现。瓣在囊腔内的正确和细致放置是该手术成功的最关键问题。

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