Cao Xiuwei, He Zishan, Guo Lin, Liu Xigang
Key Laboratory of Agricultural Water Resources, Hebei Laboratory of Agricultural Water-Saving, Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Shijiazhuang 050021, China (X.C., Z.H., L.G., X.L.); andCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China (X.C., Z.H.).
Key Laboratory of Agricultural Water Resources, Hebei Laboratory of Agricultural Water-Saving, Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Shijiazhuang 050021, China (X.C., Z.H., L.G., X.L.); andCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China (X.C., Z.H.)
Plant Physiol. 2015 Aug;168(4):1189-96. doi: 10.1104/pp.15.00230. Epub 2015 Mar 31.
The floral meristem (FM), which develops from the inflorescence meristem upon completion of the floral transition, terminates after producing a defined number of floral organs. This is in contrast to the shoot apical meristem, which is active throughout the entire life span of plants. WUSCHEL (WUS) encodes a homeodomain-containing protein and plays a critical role in shoot apical meristem, inflorescence meristem, and FM establishment and maintenance as well as FM determinacy. Although many genes have been implicated in FM determinacy through the regulation of WUS expression, precisely how these genes are coordinated to regulate WUS and consequently dictate FM fate remains unclear. Emerging lines of evidence indicate that epigenetic mechanisms, such as histone modification, chromatin remodeling, noncoding RNAs, and DNA methylation, play vital roles in meristem maintenance and termination. Here, recent findings demonstrating the involvement of the epigenetic network in the regulation of WUS expression in the context of FM determinacy are summarized and discussed.
花分生组织（FM）在花转变完成后从花序分生组织发育而来，在产生一定数量的花器官后终止发育。这与贯穿植物整个生命周期都保持活跃的茎尖分生组织形成对比。WUSCHEL（WUS）编码一种含同源结构域的蛋白质，在茎尖分生组织、花序分生组织以及花分生组织的建立、维持和花分生组织的决定性方面发挥关键作用。尽管许多基因通过调控WUS表达参与了花分生组织的决定性，但这些基因如何精确协调以调控WUS从而决定花分生组织的命运仍不清楚。新出现的证据表明，表观遗传机制，如组蛋白修饰、染色质重塑、非编码RNA和DNA甲基化，在分生组织的维持和终止中起着至关重要的作用。在此，总结并讨论了近期关于在花分生组织决定性背景下表观遗传网络参与调控WUS表达的研究发现。
