Oppelt Peter, Betbadal Anthony, Nayak Lalitha
Case Western Reserve University, Cleveland, OH, USA
Case Western Reserve University, Cleveland, OH, USA.
Vasc Med. 2015 Apr;20(2):153-61. doi: 10.1177/1358863X14568705.
Treatment of cancer patients with antineoplastic agents is associated with a heightened risk of thrombotic events, both arterial and venous. In this article, we review the specific agents that are implicated and the pathophysiological processes that are known to be associated with this prothrombotic state. We conclude with current recommendations for prophylactic antithrombotic therapy in these clinical situations.
使用抗肿瘤药物治疗癌症患者会增加动脉和静脉血栓形成事件的风险。在本文中,我们回顾了与之相关的特定药物以及已知与这种血栓前状态相关的病理生理过程。最后,我们给出了在这些临床情况下预防性抗血栓治疗的当前建议。