一名青少年男性因甲状旁腺功能减退症诊断延迟出现反复癫痫发作、智力发育迟缓及广泛脑钙化。

Recurrent seizures, mental retardation and extensive brain calcinosis related to delayed diagnosis of hypoparathyroidism in an adolescent boy.

作者信息

Eom Tae-Hoon, Kim Young-Hoon, Kim Jung-Min

机构信息

Department of Pediatric Neurology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Department of Pediatric Neurology, College of Medicine, The Catholic University of Korea, 271 Cheonbo Street, Uijeongbu, Gyeonggi-do 480-717, Republic of Korea.

出版信息

J Clin Neurosci. 2015 May;22(5):894-6. doi: 10.1016/j.jocn.2014.11.020. Epub 2015 Mar 30.

DOI:10.1016/j.jocn.2014.11.020

PMID:25835143

Abstract

Reports of adolescent patients presenting with intractable seizures and mental retardation secondary to idiopathic hypothyroidism are uncommon in the literature. In this case, we report a 17-year-old boy who developed recurrent seizures, mental retardation and extensive brain calcinosis related to delayed diagnosis of hypoparathyroidism. Hypoparathyroidism can be easily missed in children and adolescents, and may lead to irreversible neurologic sequelae. This case highlights the need to consider hypocalcemia in any patient with uncontrolled seizures.

摘要

青少年患者因特发性甲状腺功能减退继发难治性癫痫和智力发育迟缓的报道在文献中并不常见。在本病例中，我们报告一名17岁男孩，他因甲状旁腺功能减退诊断延迟而出现反复癫痫发作、智力发育迟缓及广泛脑钙化。甲状旁腺功能减退在儿童和青少年中很容易被漏诊，并可能导致不可逆的神经后遗症。该病例强调了对于任何癫痫控制不佳的患者都需要考虑低钙血症。