de Vries Marieke, Geurts Hilde
Brain and Cognition, Department of Psychology, University of Amsterdam, Weesperplein 4, 1018 XA, Amsterdam, The Netherlands,
J Autism Dev Disord. 2015 Sep;45(9):2734-43. doi: 10.1007/s10803-015-2438-1.
Children with Autism Spectrum Disorders (ASDs) often experience a low Quality of Life (QoL). We studied if IQ, early language development, current autism traits, and daily Executive Functions (EFs) are related to QoL in children (aged 8-12 years) with ASD (N = 120) and typically developing (TD) children (N = 76). Children with ASD showed a lower QoL than TD children. This lower QoL was related to higher levels of autism traits and EF deficits. Moreover, specific autism traits and EFs were related to specific QoL subdomains. The low QoL and the aggravating effects of autism traits and EF deficits indicate a potential to identify and target such factors in treatment to improve QoL.
患有自闭症谱系障碍（ASD）的儿童通常生活质量较低。我们研究了智商、早期语言发展、当前的自闭症特征以及日常执行功能（EF）是否与患有ASD的儿童（8至12岁，N = 120）和发育正常（TD）的儿童（N = 76）的生活质量相关。患有ASD的儿童的生活质量低于TD儿童。这种较低的生活质量与较高水平的自闭症特征和EF缺陷有关。此外，特定的自闭症特征和EF与特定的生活质量子领域相关。低生活质量以及自闭症特征和EF缺陷的加重作用表明，在治疗中识别和针对这些因素以提高生活质量具有潜力。
