Rundell Sean D, Gellhorn Alfred C, Comstock Bryan A, Heagerty Patrick J, Friedly Janna L, Jarvik Jeffrey G
Department of Rehabilitation Medicine, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA; Comparative Effectiveness, Cost, and Outcomes Research Center, University of Washington, 4333 Brooklyn Ave NE, Seattle, WA 98105, USA.
Department of Rehabilitation and Regenerative Medicine, Weill Cornell Medical Center, 525 E 68th St, New York, NY 10021, USA.
Spine J. 2015 Aug 1;15(8):1744-55. doi: 10.1016/j.spinee.2015.04.001. Epub 2015 Apr 4.
The timing of physical therapy (PT) services and its association with later function and pain are not clear, especially in older adults.
The purpose of this study was to compare clinical outcomes of patients receiving early or later PT services with those not receiving PT among older adults presenting to primary care for a new visit for back pain.
STUDY DESIGN/SETTING: Prospective cohort study using the Back Pain Outcomes Using Longitudinal Data registry.
A total of 3,705 adults 65 years and older with a new visit for back pain were included.
The outcome measures were Roland-Morris Disability Questionnaire (RMDQ), Pain Numerical Rating Scales, and EuroQol-5D.
We studied two phases of PT utilization: early (0-28 days) and later (3-6 months). At baseline, we selected the participants with complete 12 months of patient-reported outcomes and electronic medical record data. Early PT was defined as initiating PT less than or equal to 28 days from the index visit for back pain. The no early PT group consisted of patients with no PT, no injections, no surgery, and no chiropractic within 28 days. We restricted the later phase analysis to patients with pain greater than 2 of 10 and an RMDQ score greater than 4 to create a subsample of patients with continuing clinically important back pain. We defined later PT as initiating PT between 3 and 6 months after the index visit. The no later PT group consisted of patients without any PT during this time. We used propensity score matching followed by multiple linear regression to estimate the mean difference in outcome. Sensitivity analysis examined clinically important change and dose of PT use among the early PT group.
The early PT group had better functional status with an adjusted mean RMDQ of 1.1 points less than the no early PT group (95% confidence interval: -2.2, -0.1) and less back pain of -0.5 (-0.9, -0.1) at 12 months. There was no difference between early PT groups at 3 and 6 months. The odds of a 30% improvement in function or pain were not different between these matched groups at 12 months, but the early PT group had increased odds of a 50% improvement in function at 12 months (odds ratio: 1.58, 95% confidence interval: 1.04, 2.40). There was no difference between later groups at 12 months. Greater dose of PT use within the early PT group was associated with better functional status (p= .01).
We found that among older adults presenting to their primary care providers for a new episode of back pain, early referral to PT resulted in no or minimal differences in pain, function, or health-related quality at 3, 6, or 12 months compared with a matched group that did not receive early PT. Secondary analysis show that patients initiating early PT may be somewhat more likely to experience 50% improvement in function at 12 months.
物理治疗(PT)服务的时机及其与后期功能和疼痛的关联尚不清楚,尤其是在老年人中。
本研究的目的是比较在初级保健机构因新发背痛就诊的老年人中,接受早期或晚期PT服务的患者与未接受PT服务的患者的临床结局。
研究设计/设置:使用纵向数据的背痛结局登记处进行的前瞻性队列研究。
共纳入3705名65岁及以上因新发背痛就诊的成年人。
结局指标为罗兰-莫里斯残疾问卷(RMDQ)、疼痛数字评分量表和欧洲五维健康量表(EuroQol-5D)。
我们研究了PT使用的两个阶段:早期(0-28天)和晚期(3-6个月)。我们选择了具有完整12个月患者报告结局和电子病历数据的参与者。早期PT定义为从背痛指数就诊起28天内开始接受PT。未早期接受PT组包括在28天内未接受PT、未注射、未手术且未接受整脊治疗的患者。我们将后期分析限制在疼痛评分大于10分中的2分且RMDQ评分大于4分的患者,以创建具有持续临床重要性背痛的患者子样本。我们将晚期PT定义为在指数就诊后3至6个月开始接受PT。未晚期接受PT组包括在此期间未接受任何PT的患者。我们使用倾向得分匹配,然后进行多元线性回归来估计结局的平均差异。敏感性分析检查了早期PT组中具有临床重要意义的变化和PT使用剂量。
早期PT组在12个月时功能状态更好,调整后的平均RMDQ比未早期接受PT组低1.1分(95%置信区间:-2.2,-0.1),背痛减轻0.5分(-0.9,-0.1)。在3个月和6个月时,早期PT组之间没有差异。在这些匹配组中,12个月时功能或疼痛改善30%的几率没有差异,但早期PT组在12个月时功能改善50%的几率增加(优势比:1.58,95%置信区间:1.04,2.40)。12个月时晚期组之间没有差异。早期PT组中更大剂量的PT使用与更好的功能状态相关(p = 0.01)。
我们发现,在因新发背痛就诊于初级保健提供者的老年人中,与未早期接受PT的匹配组相比,早期转诊至PT在3、6或12个月时疼痛、功能或健康相关生活质量方面没有差异或差异最小。二次分析表明,早期开始接受PT的患者在12个月时功能改善50%的可能性可能略高。