大的无蒂锯齿状息肉内镜下黏膜切除术（EMR）后的复发率
Recurrence rates after EMR of large sessile serrated polyps.
作者信息
Rex Kevin D, Vemulapalli Krishna C, Rex Douglas K
机构信息
Division of Gastroenterology/Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
出版信息
Gastrointest Endosc. 2015 Sep;82(3):538-41. doi: 10.1016/j.gie.2015.01.025. Epub 2015 Apr 4.
BACKGROUND
Little is known regarding the recurrence rate after EMR of large (≥20 mm) sessile serrated adenoma/polyps (SSA/Ps).
OBJECTIVE
To compare the recurrence rate among SSA/Ps and conventional adenomas in patients referred to a specialty practice for EMR.
DESIGN
Retrospective cohort study.
SETTING
Academic hospital and a satellite surgery center.
PATIENTS
A total of 362 consecutive patients referred for resection of large (≥20 mm) polyps in the colorectum.
INTERVENTIONS
All EMRs were performed with a submucosal contrast agent. All subjects had a follow-up surveillance examination (inspection and biopsy of the EMR) at our center.
MAIN OUTCOME MEASUREMENTS
Rates of residual polyp at follow-up examination.
RESULTS
Residual polyp was identified among 8.7% of SSA/Ps compared with 11.1% for conventional adenomas (P = .8).
LIMITATIONS
Retrospective design, procedures performed by a single experienced endoscopist, low number of serrated lesions.
CONCLUSIONS
The rate of recurrence after EMR of SSA/Ps is similar to the rate after EMR of conventional adenomas.
背景
关于大的（≥20毫米）无蒂锯齿状腺瘤/息肉（SSA/P）内镜黏膜切除术（EMR）后的复发率，人们了解甚少。
目的
比较转诊至专科进行EMR的患者中SSA/P与传统腺瘤的复发率。
设计
回顾性队列研究。
地点
学术医院和一个卫星手术中心。
患者
共有362例连续转诊至我院行大肠大息肉（≥20毫米）切除术的患者。
干预措施
所有EMR均使用黏膜下造影剂进行。所有受试者均在我院接受随访监测检查（EMR部位的检查和活检）。
主要观察指标
随访检查时残留息肉的发生率。
结果
SSA/P患者中残留息肉的发生率为8.7%，而传统腺瘤患者为11.1%（P = 0.8）。
局限性
回顾性设计、由单一经验丰富的内镜医师操作、锯齿状病变数量少。
结论
SSA/P的EMR术后复发率与传统腺瘤的EMR术后复发率相似。
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