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引用本文的文献

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Attenuated psychosis syndrome: benefits of explicit recognition.减状精神病综合征:明确识别的益处
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本文引用的文献

1
Prevention: Before the break.预防:在破裂之前。
Nature. 2014 Apr 3;508(7494):S12-3. doi: 10.1038/508S12a.
2
Prodromal psychosis detection in a counseling center population in China: an epidemiological and clinical study.中国心理咨询中心人群前驱期精神病的检测:一项流行病学和临床研究。
Schizophr Res. 2014 Feb;152(2-3):391-9. doi: 10.1016/j.schres.2013.11.039. Epub 2013 Dec 30.
3
Preventing a first episode of psychosis: meta-analysis of randomized controlled prevention trials of 12 month and longer-term follow-ups.预防首发精神病:12 个月及更长时间随访的随机对照预防试验的荟萃分析。
Schizophr Res. 2013 Sep;149(1-3):56-62. doi: 10.1016/j.schres.2013.07.004. Epub 2013 Jul 18.
4
Long-term follow-up of a group at ultra high risk ("prodromal") for psychosis: the PACE 400 study.长期随访一组超高风险(“前驱期”)精神病患者:PACE 400 研究。
JAMA Psychiatry. 2013 Aug;70(8):793-802. doi: 10.1001/jamapsychiatry.2013.1270.
5
Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk.预测精神病:对临床高风险个体转变结果的荟萃分析。
Arch Gen Psychiatry. 2012 Mar;69(3):220-9. doi: 10.1001/archgenpsychiatry.2011.1472.
6
Preventing progression to first-episode psychosis in early initial prodromal states.预防首发精神病的早期前驱期向首发期进展。
Br J Psychiatry. 2012 Jan;200(1):22-9. doi: 10.1192/bjp.bp.109.066357. Epub 2011 Nov 10.
7
The psychosis threshold in Ultra High Risk (prodromal) research: is it valid?精神病阈在超高风险(前驱期)研究中的应用:是否有效?
Schizophr Res. 2010 Jul;120(1-3):1-6. doi: 10.1016/j.schres.2010.03.014. Epub 2010 Apr 8.
8
Psychotic-like experiences as overdetermined phenomena: when do they increase risk for psychotic disorder?
Schizophr Res. 2009 Mar;108(1-3):303-4. doi: 10.1016/j.schres.2008.10.006. Epub 2008 Oct 28.
9
Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up.用于检测超高危精神病个体的“前驱期”标准的验证:2年随访
Schizophr Res. 2008 Oct;105(1-3):10-7. doi: 10.1016/j.schres.2008.07.012. Epub 2008 Sep 2.
10
Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability.使用前驱综合征结构化访谈和前驱症状量表进行前驱评估:预测效度、评分者间信度以及信度训练。
Schizophr Bull. 2003;29(4):703-15. doi: 10.1093/oxfordjournals.schbul.a007040.

精神病风险综合征并非前驱性精神病。

Psychosis risk syndrome is not prodromal psychosis.

作者信息

Xu Lihua, Zhang Tianhong, Wang Jijun

机构信息

Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Shanghai Arch Psychiatry. 2015 Feb 25;27(1):42-4. doi: 10.11919/j.issn.1002-0829.214178.

DOI:10.11919/j.issn.1002-0829.214178
PMID:25852255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4372760/
Abstract

One of the most exciting trends in schizophrenia research is the shift in focus from treatment studies to studies about the early identification and prevention of schizophrenia. These studies have primarily focused on adolescents or young adults with prodromal symptoms or on clinically high-risk individuals who show similar impairments in cognitive and social functioning to those seen in individuals with schizophrenia and, thus, are considered at high risk of developing schizophrenia or other psychotic disorders. Some researchers have labeled this condition as psychosis risk syndrome (PRS). There are moves in some circles to re-define the condition as a disorder in its own right: the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders 5(th) edition (DSM-5), lists 'attenuated psychosis syndrome' (APS) in the appendix as a condition for further study. Individuals with PRS are certainly at higher risk of developing a psychotic disorder than those without PRS, but the majority of those with PRS do not subsequently develop a psychotic disorder, so we argue against the inclusion of PRS or APS as a subtype of schizophrenia spectrum disorder.

摘要

精神分裂症研究中最令人兴奋的趋势之一,是研究重点从治疗研究转向精神分裂症的早期识别和预防研究。这些研究主要集中于有前驱症状的青少年或年轻人,或临床上的高风险个体,这些个体在认知和社会功能方面表现出与精神分裂症患者类似的损害,因此被认为有很高的发展为精神分裂症或其他精神障碍的风险。一些研究人员将这种情况称为精神病风险综合征(PRS)。在一些领域,有人提议将这种情况重新定义为一种独立的疾病:美国精神病学协会的《精神疾病诊断与统计手册》第5版(DSM-5)在附录中列出了“轻度精神病综合征”(APS)作为有待进一步研究的病症。患有PRS的个体发展为精神障碍的风险肯定高于没有PRS的个体,但大多数患有PRS的人随后并未发展为精神障碍,因此我们反对将PRS或APS纳入精神分裂症谱系障碍的亚型。