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大网膜妊娠:病例报告及文献综述

Omental pregnancy: case report and review of literature.

作者信息

Maiorana Antonio, Incandela Domenico, Giambanco Laura, Alio Walter, Alio Luigi

机构信息

Gynecology and Obstetrics Unit, Palermo Civic Hospital and National Center of Clinical Excellence (ARNAS Di Cristina-Benfratelli), Palermo, Italy.

出版信息

Pan Afr Med J. 2014 Nov 5;19:244. doi: 10.11604/pamj.2014.19.244.3661. eCollection 2014.

Abstract

Pregnancy, the implantation of a fertilized ovum outside the endometrial cavity, occurs in 1.5%-2% of pregnancies. It is one of the major causes (about 6%) of maternal death during the first trimester of pregnancy. The remaining 5% implant in the ovary, peritoneal cavity, within the cervix, and the omental pregnancy is the least common form of abdominal pregnancies. A review of the literature on Medline for the period 1958-2012 reported only 16 cases of omental pregnancy. Here we report a case of primary omental pregnancy in a nulliparous woman. A 24 year-old woman gravid 1, para 0, with lower abdominal pain. Her last menstrual period occurred 8 weeks before the visit. The physical examination revealed abdominal tenderness in the lower quadrants, she was not bleeding. Transvaginal ultrasound showed: a free anechoic/hypoechoic area of 30 x 57 mm in the pouch of Douglas and the endometrium was homogeneus with a thickness of 12 mm and no evidence of gestational sac in the uterine cavity. Laboratory data revealed a normal cell blood count and beta hcg levels of 8047 IU / L. Because of continuing abdominal pain and a diagnosis of ectopic pregnancy a diagnostic laparoscopy was performed, which showed hemoperitoneum. Further inspection of abdominal cavity revealed a bloody lesion that was tenaciously adherent to the omentum, using non traumatic laparoscopic forceps and bipolar scissors we carefully removed a friable mass of about 30 mm from the omental attachments. Histological examination showed the presence of blood clot material mixed with trophoblastic tissue. Ultrasound evaluation and and hCG assessment are important to determine the extrauterine location of the ectopic pregnancy but the early diagnosis of abdominal pregnancy requires also a laparoscopic evaluation and, as our case has highlighted, thorough abdominal exploration especially in the absence of adnexal findings when ectopic pregnancy is highly suspected. Early diagnosis of omental pregnancy is difficult but essential to reduce the high mortality risk for the mother.

摘要

宫外孕,即受精卵在子宫内膜腔外着床,发生率为1.5%-2%。它是妊娠头三个月孕产妇死亡的主要原因之一(约占6%)。其余5%的宫外孕着床于卵巢、腹腔、宫颈内,而大网膜妊娠是腹腔妊娠最不常见的形式。对1958年至2012年期间Medline上的文献进行回顾,仅报道了16例大网膜妊娠病例。在此,我们报告一例初产妇原发性大网膜妊娠病例。一名24岁女性,孕1产0,有下腹痛。她的末次月经在就诊前8周。体格检查发现下腹部象限有压痛,无出血。经阴道超声显示:Douglas腔有一个30×57mm的无回声/低回声区,子宫内膜均匀,厚度为12mm,宫腔内未见妊娠囊。实验室检查显示血细胞计数正常,β-hCG水平为8047IU/L。由于持续腹痛且诊断为宫外孕,进行了诊断性腹腔镜检查,发现有腹腔积血。进一步检查腹腔发现一个血性病变,紧密附着于大网膜,我们使用无创腹腔镜钳和双极剪刀小心地从大网膜附着物上切除了一个约30mm的易碎肿块。组织学检查显示有血凝块物质与滋养层组织混合。超声评估和hCG检测对于确定宫外孕的宫外位置很重要,但腹腔妊娠的早期诊断还需要腹腔镜评估,正如我们的病例所强调的,尤其是在高度怀疑宫外孕但附件无异常发现时,需要进行全面的腹腔探查。大网膜妊娠的早期诊断困难,但对于降低母亲的高死亡风险至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5a7/4382054/1e9d7a944c77/PAMJ-19-244-g001.jpg

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