埃塞俄比亚贡德尔尸检患者的冠状动脉粥样硬化和心肌梗死
Coronary atherosclerosis and myocardial infarction in autopsied patients in Gondar, Ethiopia.
作者信息
Maru M
机构信息
Department of Internal Medicine, Gondar College of Medical Sciences, Addis Ababa University, Ethiopia.
出版信息
J R Soc Med. 1989 Jul;82(7):399-401. doi: 10.1177/014107688908200710.
Autopsy study of 124 Ethiopian patients for atherosclerotic lesions and myocardial infarction revealed aortic lesions in 58 (47%), coronary lesions in 26 (21%) and myocardial infarction in 8 (6.5%) cases. Fatty streaks in the coronary arteries were detected after the age of 19 years. Thereafter the frequency increased gradually with age reaching a peak of 33.3% by the age group of 50-59 years. Fibrous plaque appeared at the age of 40 years and progressed with age reaching a maximum of 44.4% by the age of 60-69 years. Myocardial infarction was the cause of sudden death in two cases. Six of the patients with myocardial infarction had moderate to severe lesions. Calcification with narrowing of the left anterior descending coronary artery was found in a 60-year-old female. The significance of the increasing incidence of CHD in black Africans and particularly in Ethiopians is discussed.
对124名埃塞俄比亚患者进行的动脉粥样硬化病变和心肌梗死尸检研究显示，58例（47%）有主动脉病变，26例（21%）有冠状动脉病变，8例（6.5%）有心肌梗死。冠状动脉脂肪条纹在19岁以后被检测到。此后，其发生率随年龄逐渐增加，在50 - 59岁年龄组达到峰值33.3%。纤维斑块出现在40岁，随年龄进展，在60 - 69岁时达到最高44.4%。心肌梗死是两例猝死的原因。6例心肌梗死患者有中度至重度病变。在一名60岁女性中发现左前降支冠状动脉钙化并狭窄。讨论了黑非洲人尤其是埃塞俄比亚人冠心病发病率上升的意义。
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