Ropponen J, Vainikka T, Sinisalo J, Rapola J, Laine M, Ihlberg L
Department of Cardiac Surgery, Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland.
Department of Cardiology, Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland.
Scand J Surg. 2016 Mar;105(1):35-41. doi: 10.1177/1457496915575832. Epub 2015 Apr 8.
In this report, we present our experience with the transaortic transcatheter aortic valve implantation using the SAPIEN valve. The procedural success, 30-day outcome, and survival up to 2 years are compared with the transapical access performed in patients in our institution.
Of a total of 282 transcatheter aortic valve implantation patients, 100 consecutive patients had a non-transfemoral approach. The transaortic and transapical access routes were used in 36 and 64 patients, respectively. The transaortic group had a higher mean logistic EuroSCORE (32.6 vs 25.2, p = 0.021) and more patients with left ventricular ejection fraction less than 40% (33.3% vs 14.1%, p = 0.023).
The respective technical success rates for the transaortic and transapical groups were 100% and 95.2% (p = NS). There were significantly more perioperative hemodynamic problems necessitating cardiopulmonary resuscitation or mechanical circulatory support in the transapical group (18.8% vs 2.8%, p = 0.023). The transaortic group had a slightly shorter hospital stay (7 vs 8 days, p = 0.018). The 30-day mortality was 8.6% and 10.9% in the transaortic and transapical group, respectively (p = NS). Combined safety outcome was similar in both groups at 30 days. The respective 1-year survival rates for the transaortic and transapical groups were 71.5% and 68.3%, respectively (p = NS).
The trans transcatheter aortic valve implantation is a considerable choice to transapical approach. Despite a higher risk patient cohort, the clinical outcome is at least comparable to the transapical transcatheter aortic valve implantation, and it can be utilized as a second choice for patients with prohibitive iliac-femoral anatomy for transfemoral access.
在本报告中,我们介绍了使用SAPIEN瓣膜经主动脉进行经导管主动脉瓣植入术的经验。将手术成功率、30天结局以及长达2年的生存率与本机构中患者行经心尖入路的情况进行比较。
在总共282例经导管主动脉瓣植入患者中,100例连续患者采用了非经股动脉入路。经主动脉和经心尖入路分别应用于36例和64例患者。经主动脉组的平均逻辑欧洲心脏手术风险评估系统(EuroSCORE)评分较高(32.6对25.2,p = 0.021),且左心室射血分数低于40%的患者更多(33.3%对14.1%,p = 0.023)。
经主动脉组和经心尖组各自的技术成功率分别为100%和95.2%(p = 无统计学意义)。经心尖组围手术期需要心肺复苏或机械循环支持的血流动力学问题明显更多(18.8%对2.8%,p = 0.023)。经主动脉组的住院时间略短(7天对8天,p = 0.018)。经主动脉组和经心尖组的30天死亡率分别为8.6%和10.9%(p = 无统计学意义)。两组在30天时的综合安全结局相似。经主动脉组和经心尖组各自的1年生存率分别为71.5%和68.3%(p = 无统计学意义)。
经导管主动脉瓣植入术是经心尖入路的一个相当不错的选择。尽管患者队列风险较高,但临床结局至少与经心尖经导管主动脉瓣植入术相当,并且它可作为因髂股解剖结构不利于经股动脉入路的患者的第二选择。