Massmann Alexander, Jagoda Philippe, Kranzhoefer Nicole, Buecker Arno
Clinic of Diagnostic and Interventional Radiology, Saarland University Medical Center, Homburg/Saar, Germany.
Clinic of Internal Medicine, Oncology, Hematology, Immunology and Rheumatology, Saarland University Medical Center, Homburg/Saar, Germany.
Ann Surg Oncol. 2015 Dec;22(13):4124-9. doi: 10.1245/s10434-015-4549-5. Epub 2015 Apr 9.
Observational analysis of percutaneous repositioning of displaced port-catheters in patients with dysfunctional central-venous port-systems.
A total of 1061 patients with dysfunctional venous pectoral port-systems were referred for port-angiography. Dislocated port-catheters were identified in 37 (3.5 %) patients (11 males, mean age 58.1 ± 7.2 [range 48-69] years; 26 females, 57.0 ± 13.5 [range 24-75] years) 3.9 ± 6.6 months (range 1 day-26 months) after port-implantation. Percutaneous repositioning in all patients was performed by transfemoral catheter maneuvers, snaring, or wire-assisted long-loop snaring. Primary endpoint was successful repositioning. Safety endpoints included port-damage or procedure-related complications. Follow-up encompassed routine clinical and radiological controls, including chest X-ray or computed tomography for 12.9 ± 17.9 (range 1-81) months.
Clinical signs of port-dysfunction due to dislocation of port-catheters included difficult aspiration in 23 (62.2 %), resistance or inability to inject in 17 (46.0 %), and pain during injection in 2 (5.4 %) patients. Primary technical success for repositioning displaced port-catheters was 97.3 % (36/37 patients). In 1 (2.7 %) patient, repositioning failed due to complete embedding of the port-catheter in an extensive chronic jugular vein thrombosis (Paget-von-Schroetter syndrome) that prevented endovascular access to the port-catheter. Redisplacement occurred after initial successful repositioning: immediately in two patients due to a too short port-catheter (two-tailed Fisher's exact-test, p = 0.0101), and in two patients with appropriate catheter-length after 5, resp. 7 months. No procedure-associated complications, e.g., port-catheter disconnection or disruption, occurred.
Repositioning of dysfunctional displaced central-venous port-catheters with appropriate catheter-length is safe and effective. Even challenging conditions, e.g., wall-adherent port-catheter tip or a thrombosed catheter-bearing vein are feasible. Repositioning of too short port-catheters is ineffective.
对功能失调的中心静脉端口系统患者的移位端口导管进行经皮重新定位的观察性分析。
共有1061例功能失调的静脉胸段端口系统患者接受了端口血管造影检查。在37例(3.5%)患者中发现端口导管移位(11例男性,平均年龄58.1±7.2岁[范围48 - 69岁];26例女性,57.0±13.5岁[范围24 - 75岁]),在植入端口后3.9±6.6个月(范围1天 - 26个月)。所有患者均通过经股动脉导管操作、圈套或钢丝辅助长环圈套进行经皮重新定位。主要终点是成功重新定位。安全终点包括端口损伤或与操作相关的并发症。随访包括常规临床和放射学检查,包括胸部X线或计算机断层扫描,为期12.9±17.9个月(范围1 - 81个月)。
因端口导管移位导致的端口功能失调的临床体征包括23例(62.2%)抽吸困难、17例(46.0%)注射时有阻力或无法注射、2例(5.4%)患者注射时疼痛。移位端口导管重新定位的主要技术成功率为97.3%(36/37例患者)。1例(2.7%)患者因端口导管完全嵌入广泛的慢性颈静脉血栓形成(Paget - von - Schroetter综合征)而无法进行血管内通路,导致重新定位失败。最初成功重新定位后发生了重新移位:2例患者因端口导管过短立即发生(双侧Fisher精确检验,p = 0.0101),2例导管长度合适的患者分别在5个月和7个月后发生。未发生与操作相关的并发症,如端口导管断开或破裂。
对功能失调的移位中心静脉端口导管进行具有合适导管长度的重新定位是安全有效的。即使是具有挑战性的情况,如端口导管尖端贴壁或带导管的静脉血栓形成也是可行的。重新定位过短的端口导管是无效的。