Rubinstein Jill C, Liu Lucy, Caty Michael G, Christison-Lagay Emily R
Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
J Pediatr Surg. 2015 Oct;50(10):1665-7. doi: 10.1016/j.jpedsurg.2015.03.048. Epub 2015 Mar 26.
Historically, the rate of pathologic leadpoints in older children with intussusception is quoted as 20%-25%. Our anecdotal experience suggested a lower rate. We therefore compiled a case series to examine the actual incidence of pathologic leadpoint, and treatment success, by age.
A retrospective review was performed of all patients admitted with intussusception between 1998 and 2012 and tested for differences in anatomic location, presence of pathologic leadpoint, and need for operative intervention, on the basis of age.
In total, 154 cases of intussusception were diagnosed in 141 patients (136 ileo-colic), 38 of which were in children older than 3 (29 ileo-colic). Considering all anatomic locations, older children were more likely to have a pathologic leadpoint (p-value 0.01); however subgroup analysis of ileo-colic intussusception demonstrated no difference (p-value 0.38). Additionally, there was no difference in the success of pneumatic or barium enema reduction on the basis of age (p-value 0.56).
Despite historical reports of increased pathologic leadpoints in ileo-colic intussusception in older children, in this series the majority were idiopathic. Non-operative management was successful approximately 75% of the time, irrespective of age. In older age groups, there was an increased frequency of pathologic leadpoints in small bowel-small bowel intussusception.
在历史上,年龄较大的肠套叠患儿中病理性引导点的发生率被认为是20%-25%。我们的经验表明发生率较低。因此,我们汇总了一个病例系列,以按年龄检查病理性引导点的实际发生率和治疗成功率。
对1998年至2012年间所有因肠套叠入院的患者进行回顾性研究,并根据年龄对解剖位置、病理性引导点的存在情况以及手术干预的必要性进行差异检测。
总共141例患者诊断出154例肠套叠(136例回结肠型),其中38例发生在3岁以上儿童(29例回结肠型)。考虑所有解剖位置,年龄较大的儿童更有可能有病理性引导点(p值0.01);然而,回结肠型肠套叠的亚组分析显示无差异(p值0.38)。此外,基于年龄,空气灌肠或钡剂灌肠复位的成功率没有差异(p值0.56)。
尽管历史报道显示年龄较大儿童的回结肠型肠套叠中病理性引导点增加,但在本系列中大多数是特发性的。非手术治疗约75%的情况下成功,与年龄无关。在年龄较大的组中,小肠-小肠型肠套叠中病理性引导点的频率增加。