A unique acute myeloid leukemia patient with cryptic NUP98-NSD1 gene and ASXL1 mutation.

Suppr

超能文献

作者信息

Cui Jiangxia, Xie Jundan, Qin Lili, Chen Suning, Zhao Yun, Wu Deipei

机构信息

a Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University , Suzhou , P.R. China.

b Collaborative Innovation Center of Hematology, Soochow University , Suzhou , P.R. China.

出版信息

Leuk Lymphoma. 2016;57(1):196-8. doi: 10.3109/10428194.2015.1037755. Epub 2015 Sep 10.

DOI:10.3109/10428194.2015.1037755

PMID:25860235

Abstract

摘要

相似文献

A unique acute myeloid leukemia patient with cryptic NUP98-NSD1 gene and ASXL1 mutation.

Leuk Lymphoma. 2016;57(1):196-8. doi: 10.3109/10428194.2015.1037755. Epub 2015 Sep 10.

Chimeric NUP98-NSD1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia.

Leuk Lymphoma. 2018 Mar;59(3):725-732. doi: 10.1080/10428194.2017.1357174. Epub 2017 Aug 4.

NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia.

Genes Chromosomes Cancer. 2013 Jul;52(7):683-93. doi: 10.1002/gcc.22064. Epub 2013 Apr 30.

[Genetic characteristics and clinical outcomes of pediatric acute myeloid leukemia with NUP98-NSD1 fusion gene].

Zhonghua Yi Xue Za Zhi. 2019 Sep 24;99(36):2820-2825. doi: 10.3760/cma.j.issn.0376-2491.2019.36.005.

Identification of MYC mutations in acute myeloid leukemias with NUP98-NSD1 translocations.

Leukemia. 2016 Jul;30(7):1621-4. doi: 10.1038/leu.2016.19. Epub 2016 Feb 9.

A cryptic translocation leading to NUP98-PHF23 fusion in AML.

Best Pract Res Clin Haematol. 2016 Dec;29(4):320-323. doi: 10.1016/j.beha.2016.10.002. Epub 2016 Oct 18.

A new acute myeloid leukemia case with STAT5B-RARA gene fusion due to 17q21.2 interstitial deletion.

Leuk Lymphoma. 2017 Aug;58(8):1977-1980. doi: 10.1080/10428194.2016.1262952. Epub 2016 Dec 2.

NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.

Leukemia. 2017 Mar;31(3):565-572. doi: 10.1038/leu.2016.267. Epub 2016 Oct 3.

Clinical features of patients with acute myeloid leukaemia and the NUP98::NSD1 fusion gene.

Int J Lab Hematol. 2023 Aug;45(4):589-591. doi: 10.1111/ijlh.14032. Epub 2023 Feb 7.

NUP98-HOXA9 bearing therapy-related myeloid neoplasm involves myeloid-committed cell and induces HOXA5, EVI1, FLT3, and MEIS1 expression.

Int J Lab Hematol. 2016 Feb;38(1):64-71. doi: 10.1111/ijlh.12435. Epub 2015 Sep 29.

引用本文的文献

NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunities.

Hemasphere. 2024 Sep 25;8(9):e70013. doi: 10.1002/hem3.70013. eCollection 2024 Sep.

Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies.

Blood. 2020 Nov 12;136(20):2275-2289. doi: 10.1182/blood.2020007093.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验