心脏胸外科手术后胸骨伤口预防性抗生素给药：回顾性研究。
Prophylactic antibiotic administration for post cardiothoracic surgery sternal wounds: a retrospective study.
机构信息
1 Pulmonary Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 2 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 3 2nd Pulmonary Clinic of "Sotiria" Hospital, Athens, Greece ; 4 Pulmonary Laboratory of Alexandra Hospital University of Athens, Athens, Greece ; 5 Nuclear Medicine Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece ; 6 Thoracic Surgery Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
出版信息
Ann Transl Med. 2015 Mar;3(4):56. doi: 10.3978/j.issn.2305-5839.2015.03.22.
BACKGROUND
Cardiothoracic surgery sternal infections are difficult to treat situations. Until now there are no clear guidelines which or if an antibiotic could be used as prophylactic treatment.
PATIENTS AND METHODS
We collected retrospectively data from 535 patients from our hospital which underwent cardiothoracic surgery and recorded several biological parameters and technical aspects of the surgery.
RESULTS
It was observed that patients to whom vancomycin was administered had less post surgery infection than those to whom begalin was administered. Male who were treated with vancomycin it was observed that they had 1.67 chances to be treated properly than female. Patients which were hospitalized for more than 7 days before surgery had 62.6% higher chances for post surgery infection.
CONCLUSIONS
It was observed that vancomycin can be used as a prophylactic treatment for cardiothoracic surgeries acting efficiently against sternal wounds.
背景
心胸外科手术胸骨感染是难以治疗的情况。到目前为止，还没有明确的指南规定是否可以使用抗生素作为预防性治疗。
患者和方法
我们从我院接受心胸外科手术的 535 名患者中回顾性地收集数据，并记录了几项生物学参数和手术的技术方面。
结果
观察到给予万古霉素的患者术后感染少于给予贝拉美辛的患者。接受万古霉素治疗的男性比女性更有可能得到正确治疗，几率为 1.67 倍。手术前住院超过 7 天的患者术后感染的几率增加 62.6%。
结论
观察到万古霉素可作为心胸外科手术的预防性治疗，对胸骨伤口有效。
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