Miyano T, Ohya T, Kimura K, Arai T, Shimomura H, Yamataka A, Fukunaga K
Department of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 1989 Sep;90(9):1343-7.
Current state of the treatment of biliary atresia was studied concerning following factors based on our experience of 240 patients during 1966 to 1988, particularly 103 patients who received Kasai operation with Suruga II modification. 1. Operative results: Overall and Suruga II. 2. Predictable factors of the prognosis at the first radical operation, especially, among the age, the hepatic fibrosis and the size of ductuli at porta hepatis. 3. Technical refinement of Kasai operation, especially concerning the exposure of portal area and the anastomosis. 4. Our recent device of modified Kasai operation, that is, hepatic portoduodenostomy with interposition of ileocecoappendix. 5. Rehepatic portoenterostomy in case of poor postoperative bile flow. From our experiences, Kasai operation is indicated to the patients who have mild or moderate liver fibrosis and good sized ductuli at porta hepatis, but not to the patients who have advanced liver fibrosis and extremely poor ductuli. In such circumstance, liver transplantation should be considered. Rehepatic portoenterostomy is only indicated to the patients who have a good bile flow after the initial Kasai operation but not to the patients who have no bile flow.
基于1966年至1988年间240例患者的经验,特别是103例行改良的骏河II式Kasai手术的患者,我们研究了胆道闭锁治疗的现状,涉及以下因素。1. 手术结果:总体结果及骏河II式手术结果。2. 首次根治性手术预后的可预测因素,特别是年龄、肝纤维化程度和肝门部小胆管大小。3. Kasai手术的技术改进,特别是关于肝门区域的暴露和吻合。4. 我们最近改良的Kasai手术方法,即带回盲部阑尾间置的肝门十二指肠吻合术。5. 术后胆汁引流不佳时的再次肝门肠吻合术。根据我们的经验,Kasai手术适用于肝纤维化程度较轻或中度且肝门部小胆管大小良好的患者,而不适用于肝纤维化严重且小胆管极差的患者。在这种情况下,应考虑肝移植。再次肝门肠吻合术仅适用于初次Kasai手术后胆汁引流良好的患者,而不适用于无胆汁引流的患者。