de Jong K P, Blankensteijn J D, Hesselink E J, Laméris J S, Terpstra O T
Ned Tijdschr Geneeskd. 1989 Dec 2;133(48):2385-8.
In this retrospective study, we analyse the results of 94 partial liver resections performed between 1972 and January 1989. The resections were performed for malignant (48 patients) and benign (46 patients) liver tumours. Nine patients (9.6%) died of resection-related complications. Mortality was significantly lower in the patients with resections for benign liver tumours (2.2%) compared with patients with resections for malignant liver tumours (16.7%) (p less than 0.05). In the patients who survived the first 30 days, complications occurred in 25.9%. The 5-year survival of patients with a primary malignant liver tumour (57%) is significantly (p = 0.05) better than in patients with a secondary malignant liver tumour (19%). From this study we conclude that partial liver resections for primary or secondary liver tumours can be performed with an acceptable mortality and morbidity, and should be the therapy of choice for selected patients.
在这项回顾性研究中,我们分析了1972年至1989年1月期间进行的94例部分肝切除术的结果。这些切除术针对恶性(48例患者)和良性(46例患者)肝肿瘤进行。9例患者(9.6%)死于与手术相关的并发症。与恶性肝肿瘤切除术患者(16.7%)相比,良性肝肿瘤切除术患者的死亡率(2.2%)显著更低(p<0.05)。在度过最初30天的患者中,并发症发生率为25.9%。原发性恶性肝肿瘤患者的5年生存率(57%)显著高于继发性恶性肝肿瘤患者(19%)(p = 0.05)。从本研究中我们得出结论,针对原发性或继发性肝肿瘤的部分肝切除术可以在可接受的死亡率和发病率情况下进行,并且应该成为特定患者的首选治疗方法。