Darvishi Mohammad, Ziari Katayoun, Mohebbi Hossein, Alizadeh Kamyab
Department of Infectious Diseases, AJA University of Medical Sciences, Tehran, Iran.
Department of Pathology, Be'sat Hospital, AJA University of Medical Sciences, Tehran, Iran.
Acta Med Iran. 2015;53(4):220-4.
This study was conducted to evaluate the association between H. pylori infection and Iron deficiency anemia (IDA) among preschool children (age range: 40-75 months) at a tertiary referral hospital in Tehran.In a case-control study, the prevalence of H. pylori seropositivity was compared between 64 children with IDA diagnosis and 70 healthy non-anemic sex- and age-matched controls. Totally, 52 (81.3%) children with IDA and 10 (14.3%) non-anemic controls had a positive antibody level for H. pylori specific IgG and the difference between two groups was statistically significant (P<0.0001). H. pylori infection had a significant high prevalence among preschool patients with IDA. Eradication of H. pylori infection is recommended for patients with refractory IDA.
本研究旨在评估德黑兰一家三级转诊医院中40至75个月大的学龄前儿童幽门螺杆菌感染与缺铁性贫血（IDA）之间的关联。在一项病例对照研究中，比较了64例确诊为IDA的儿童与70例年龄和性别匹配的健康非贫血对照者中幽门螺杆菌血清阳性的患病率。总体而言，52例（81.3%）IDA儿童和10例（14.3%）非贫血对照者的幽门螺杆菌特异性IgG抗体水平呈阳性，两组之间的差异具有统计学意义（P<0.0001）。幽门螺杆菌感染在学龄前IDA患者中的患病率显著较高。对于难治性IDA患者，建议根除幽门螺杆菌感染。
