Yung Gordon L, Craig Vanessa
University of California San Diego, 9444 Medical Center Drive, 3-030, La Jolla, CA 92037, USA.
University of California San Diego, 9444 Medical Center Drive, 3-030, La Jolla, CA 92037, USA.
Transfus Apher Sci. 2015 Apr;52(2):162-6. doi: 10.1016/j.transci.2015.02.003. Epub 2015 Feb 11.
Bronchiolitis obliterans (BO) is a rare condition characterized by narrowing of small airways. Although it can be caused by variety of conditions, most cases occur after lung and bone marrow transplantation in the form of graft-versus-host-disease and chronic rejection, respectively. Extracorporeal photopheresis (ECP) has emerged as a promising treatment for the condition, especially for BO after lung transplantation. Available data suggest that around two-thirds of patients may demonstrate either slowing or cessation of disease progression after treatment with ECP. Recent researches also provide interesting insights into possible mechanism of action of ECP in BO.
闭塞性细支气管炎（BO）是一种罕见的疾病，其特征为小气道狭窄。尽管它可由多种情况引起，但大多数病例分别以移植物抗宿主病和慢性排斥反应的形式发生在肺和骨髓移植后。体外光分离置换法（ECP）已成为治疗这种疾病的一种有前景的方法，尤其是对于肺移植后的BO。现有数据表明，约三分之二的患者在接受ECP治疗后疾病进展可能会减缓或停止。最近的研究也为ECP在BO中的可能作用机制提供了有趣的见解。
Zotero 插件