Sauser Kori, Bravata Dawn M, Hayward Rodney A, Levine Deborah A
Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts.
VHA HSR&D Stroke Quality Enhancement Research Initiative Program, Center for Health Information and Communication, Indianapolis, Indiana; Regenstrief Institute, Indianapolis, Indiana; Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1329-32. doi: 10.1016/j.jstrokecerebrovasdis.2015.02.007. Epub 2015 Apr 13.
Rapid brain imaging for ischemic stroke is important for patient outcomes. We sought to determine the proportion of ischemic stroke patients receiving brain imaging within the guideline-recommended 24 hours, and predictors of faster imaging among patients with acute symptoms.
Retrospective analysis of Veterans Health Administration (VHA) Office of Performance Measurement Stroke Special Project data. Of 3000 ischemic stroke patients, secondary samples included 649 presenting within 6 hours of onset, and 217 potentially tissue plasminogen activator (tPA)-eligible patients (onset-to-arrival time <3 hours, National Institutes of Health Stroke Scale >2). Two linear regression models examined the association between door-to-imaging time and predictors among secondary samples, accounting for clustering within hospital.
Of the 3000 ischemic stroke patients, 97.1% had brain imaging within 24 hours. Among patients presenting within 6 hours of onset, median door-to-imaging time was 59 minutes (interquartile range [IQR], 33-109). Predictors of faster door-to-imaging time included elevated arrival blood pressure and stroke center presentation. Among the potentially tPA-eligible patients, median door-to-imaging time was 52 minutes (IQR, 31-105); no significant predictors were identified.
Nearly all ischemic stroke patients at VHA hospitals have door-to-imaging time within 24 hours. There remains room for improvement for timely brain imaging among patients with acute symptom onset.
对缺血性卒中患者进行快速脑部成像对患者预后很重要。我们试图确定在指南推荐的24小时内接受脑部成像的缺血性卒中患者的比例,以及急性症状患者中成像更快的预测因素。
对退伍军人健康管理局(VHA)绩效测量办公室卒中特别项目数据进行回顾性分析。在3000例缺血性卒中患者中,二次抽样包括649例发病6小时内就诊的患者,以及217例可能符合组织纤溶酶原激活剂(tPA)治疗条件的患者(发病至到达时间<3小时,美国国立卫生研究院卒中量表>2)。两个线性回归模型检验了二次抽样中从入院到成像时间与预测因素之间的关联,并考虑了医院内部的聚类情况。
在3000例缺血性卒中患者中,97.1%在24小时内进行了脑部成像。在发病6小时内就诊的患者中,从入院到成像的中位时间为59分钟(四分位间距[IQR],33 - 109)。从入院到成像时间更快的预测因素包括入院时血压升高和在卒中中心就诊。在可能符合tPA治疗条件的患者中,从入院到成像的中位时间为52分钟(IQR,31 - 105);未发现显著的预测因素。
VHA医院中几乎所有缺血性卒中患者从入院到成像的时间都在24小时内。急性症状发作患者的及时脑部成像仍有改进空间。