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[取决于人群血型和性别的流感群体免疫指标]

[Indicators of collective immunity to influenza depending on the blood group and sex of the population].

作者信息

Naĭkhin A N, Katorgina L G, Tsaritsyna I M, Kim T N, Reznik V N, Trusov N V, Denisov G M

出版信息

Vopr Virusol. 1989 Jul-Aug;34(4):419-23.

PMID:2588551
Abstract

Immunological investigations of the time course of serum anti-HA and anti-NA antibodies against influenza A and B viruses in the female and male population with blood groups 0(I), A(II), B(III), and AB(IV) were carried out for several months. The persons with the blood group AB (IV) were shown to be most sensitive to influenza A and B. They were affected by the epidemic virus earlier and more severely than those with the other blood groups. A special method is proposed for prediction of the etiology of the forthcoming epidemic. A correlation between blood groups and titres of anti-HA but not anti-NA antibodies was observed. The view on the lack of the genetic factor influence on the affliction with influenza and antibody response in persons of different sexes is substantiated.

摘要

对具有0(I)、A(II)、B(III)和AB(IV)血型的男性和女性人群中针对甲型和乙型流感病毒的血清抗血凝素(HA)和抗神经氨酸酶(NA)抗体的时间进程进行了数月的免疫学研究。结果显示,AB(IV)血型的人对甲型和乙型流感最为敏感。他们比其他血型的人更早、更严重地受到流行病毒的影响。提出了一种预测即将到来的流行病病因的特殊方法。观察到血型与抗HA抗体滴度之间存在相关性,但与抗NA抗体滴度无关。不同性别人群中流感易感性和抗体反应缺乏遗传因素影响这一观点得到了证实。

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