HIV感染会增加全膝关节置换术后短期不良后果的风险吗？
Does HIV Infection Increase the Risk of Short-Term Adverse Outcomes Following Total Knee Arthroplasty?
作者信息
Boylan Matthew R, Basu Niladri, Naziri Qais, Issa Kimona, Maheshwari Aditya V, Mont Michael A
机构信息
Department of Orthopaedics, SUNY Downstate Medical Center, Brooklyn, New York; Department of Epidemiology and Biostatistics, SUNY Downstate Medical Center, Brooklyn, New York.
Department of Orthopaedics, SUNY Downstate Medical Center, Brooklyn, New York.
出版信息
J Arthroplasty. 2015 Sep;30(9):1629-32. doi: 10.1016/j.arth.2015.03.018. Epub 2015 Mar 31.
Using the Nationwide Inpatient Sample, we assess the: (1) demographic trends; (2) complications; and (3) length of hospital stay among total knee arthroplasty (TKA) patients with and without human immunodeficiency virus (HIV). The study population consisted of 2772 patients with HIV and 5,672,314 controls. Patients with HIV were more likely to be younger, male, and nonwhite. Patients with HIV were at an increased risk for perioperative wound infections (OR=2.78; P=0.024), although they were not at an increased risk for overall complications (OR=1.21; P=0.321). Mean length of stay was 17% longer for patients with HIV (P<0.001). Given these findings, orthopedic surgeons should have a low threshold to work up a patient with HIV for a wound infection following TKA.
利用全国住院患者样本，我们评估了：（1）人口统计学趋势；（2）并发症；以及（3）感染和未感染人类免疫缺陷病毒（HIV）的全膝关节置换术（TKA）患者的住院时间。研究人群包括2772例HIV患者和5672314例对照。HIV患者更可能较年轻、为男性且是非白人。HIV患者围手术期伤口感染风险增加（OR = 2.78；P = 0.024），尽管他们总体并发症风险未增加（OR = 1.21；P = 0.321）。HIV患者的平均住院时间长17%（P < 0.001）。鉴于这些发现，骨科医生对于TKA术后出现伤口感染的HIV患者应降低检查门槛。
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