de Oliveira Glaucia Martins, Yokomizo Juliana Emy, Vinholi e Silva Laís dos Santos, Saran Laura Ferreira, Bottino Cássio M C, Yassuda Mônica Sanches
School of Arts,Sciences and Humanities,University of São Paulo,São Paulo,Brazil.
Old Age Research Group (PROTER),Institute of Psychiatry,University of São Paulo School of Medicine,São Paulo,Brazil.
Int Psychogeriatr. 2016 Jan;28(1):93-9. doi: 10.1017/S1041610215000642. Epub 2015 Apr 29.
The Cognitive Abilities Screening Instrument - Short (CASI-S) is a brief cognitive screening test. However, there is limited information regarding its applicability in primary care.
To ascertain whether the CASI-S differentiates between dementia patients and normal controls in primary care; to examine its correlation with other cognitive instruments, to analyze its internal consistency, test-retest stability, and diagnostic accuracy.
In a case-control study, carried out at two Primary Care Units (PCUs) in the eastern region of the city of São Paulo, 47 older adults were diagnosed with dementia according to DSM-IV criteria (mean age = 76.81 ± 7.03 years), and 55 were classified as normal controls (mean age = 72.78 ± 7.37 years), by a multidisciplinary panel which had access to results from a comprehensive cognitive battery and the patients' health data. The present analyses included results from the Mini-Mental State Examination (MMSE). The CASI-S was not used to determine diagnostic status.
The CASI-S was easily applied in the primary care setting. There was a significant performance difference (p < 0.001) between dementia patients (15.57 ± 7.40) and normal controls (26.67 ± 3.52) on the CASI-S. CASI-S scores correlated with age (ρ = -0.410, p < 0.001), educational level (ρ = 0.373, p < 0.001), and MMSE score (ρ = 0.793, p < 0.001). The internal consistency of the CASI-S was high (α = 0.848) and the correlation between test and retest was 0.688, suggesting adequate temporal stability. In the ROC curve analyses, scores of 22/23 generated an area under the curve of 0.907, with sensitivity of 93% and specificity of 81%.
The CASI-S can be useful for dementia screening in primary care in Brazil.
简易认知能力筛查量表(CASI-S)是一种简短的认知筛查测试。然而,关于其在初级保健中的适用性的信息有限。
确定CASI-S在初级保健中能否区分痴呆患者和正常对照;检查其与其他认知工具的相关性,分析其内部一致性、重测稳定性和诊断准确性。
在圣保罗市东部地区的两个初级保健单位(PCU)进行的一项病例对照研究中,一个多学科小组根据DSM-IV标准诊断出47名老年人患有痴呆(平均年龄=76.81±7.03岁),55名被归类为正常对照(平均年龄=72.78±7.37岁),该小组可以获取综合认知测试结果和患者的健康数据。目前的分析包括简易精神状态检查表(MMSE)的结果。CASI-S未用于确定诊断状态。
CASI-S在初级保健环境中易于应用。痴呆患者(15.57±7.40)和正常对照(26.67±3.52)在CASI-S上的表现存在显著差异(p<0.001)。CASI-S评分与年龄(ρ=-0.410,p<0.001)、教育水平(ρ=0.373,p<0.001)和MMSE评分(ρ=0.793,p<0.001)相关。CASI-S的内部一致性较高(α=0.848),重测相关性为0.688,表明有足够的时间稳定性。在ROC曲线分析中,22/23分的曲线下面积为0.907,敏感性为93%,特异性为81%。
CASI-S可用于巴西初级保健中的痴呆筛查。