Suppr超能文献

MobileMums干预措施对增加有幼儿母亲身体活动水平的成本效益分析:基于一项随机对照试验的马尔可夫模型

The cost-effectiveness of the MobileMums intervention to increase physical activity among mothers with young children: a Markov model informed by a randomised controlled trial.

作者信息

Burn Edward, Marshall Alison L, Miller Yvette D, Barnett Adrian G, Fjeldsoe Brianna S, Graves Nicholas

机构信息

Queensland University of Technology (QUT), School of Public Health and Social Work and Institute of Health and Biomedical Innovation (IHBI), Brisbane, Queensland, Australia.

The University of Queensland, School of Population Health, Brisbane, Queensland, Australia.

出版信息

BMJ Open. 2015 Apr 29;5(4):e007226. doi: 10.1136/bmjopen-2014-007226.

Abstract

OBJECTIVES

To determine the cost-effectiveness of the MobileMums intervention. MobileMums is a 12-week programme which assists mothers with young children to be more physically active, primarily through the use of personalised SMS text-messages.

DESIGN

A cost-effectiveness analysis using a Markov model to estimate and compare the costs and consequences of MobileMums and usual care.

SETTING

This study considers the cost-effectiveness of MobileMums in Queensland, Australia.

PARTICIPANTS

A hypothetical cohort of over 36 000 women with a child under 1 year old is considered. These women are expected to be eligible and willing to participate in the intervention in Queensland, Australia.

DATA SOURCES

The model was informed by the effectiveness results from a 9-month two-arm community-based randomised controlled trial undertaken in 2011 and registered retrospectively with the Australian Clinical Trials Registry (ACTRN12611000481976). Baseline characteristics for the model cohort, treatment effects and resource utilisation were all informed by this trial.

MAIN OUTCOME MEASURES

The incremental cost per quality-adjusted life year (QALY) of MobileMums compared with usual care.

RESULTS

The intervention is estimated to lead to an increase of 131 QALYs for an additional cost to the health system of 1.1 million Australian dollars (AUD). The expected incremental cost-effectiveness ratio for MobileMums is 8608 AUD per QALY gained. MobileMums has a 98% probability of being cost-effective at a cost-effectiveness threshold of 64 000 AUD. Varying modelling assumptions has little effect on this result.

CONCLUSIONS

At a cost-effectiveness threshold of 64 000 AUD, MobileMums would likely be a cost-effective use of healthcare resources in Queensland, Australia.

TRIAL REGISTRATION NUMBER

Australian Clinical Trials Registry; ACTRN12611000481976.

摘要

目标

确定“移动妈妈”干预措施的成本效益。“移动妈妈”是一项为期12周的项目,主要通过发送个性化短信,帮助有幼儿的母亲增加身体活动量。

设计

采用马尔可夫模型进行成本效益分析,以估计和比较“移动妈妈”干预措施与常规护理的成本及结果。

背景

本研究评估了澳大利亚昆士兰州“移动妈妈”项目的成本效益。

参与者

假设为超过36000名有1岁以下孩子的女性组成的队列。预计这些女性符合条件并愿意在澳大利亚昆士兰州参与该干预措施。

数据来源

该模型依据2011年进行的一项为期9个月的双臂社区随机对照试验的有效性结果构建,并追溯注册于澳大利亚临床试验注册中心(ACTRN12611000481976)。该试验为模型队列的基线特征、治疗效果及资源利用情况提供了依据。

主要结局指标

“移动妈妈”干预措施与常规护理相比,每获得一个质量调整生命年(QALY)的增量成本。

结果

估计该干预措施可使健康产出增加131个QALY,卫生系统需额外支出110万澳元(AUD)。“移动妈妈”干预措施预期的增量成本效益比为每获得一个QALY需8608澳元。在成本效益阈值为64000澳元时,“移动妈妈”干预措施具有成本效益的概率为98%。改变模型假设对该结果影响不大。

结论

在成本效益阈值为64000澳元时,“移动妈妈”干预措施在澳大利亚昆士兰州可能是一种具有成本效益的医疗资源利用方式。

试验注册号

澳大利亚临床试验注册中心;ACTRN12611000481976。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dc9/4420940/37d396d0112e/bmjopen2014007226f01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验