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腹部大手术后的肺部并发症:国家外科质量改进计划分析

Pulmonary complications after major abdominal surgery: National Surgical Quality Improvement Program analysis.

作者信息

Yang Chun Kevin, Teng Annabelle, Lee David Y, Rose Keith

机构信息

Department of Surgery, Mount Sinai St. Luke's Hospital and Mount Sinai Roosevelt Hospital, New York.

Department of Surgery, Mount Sinai St. Luke's Hospital and Mount Sinai Roosevelt Hospital, New York.

出版信息

J Surg Res. 2015 Oct;198(2):441-9. doi: 10.1016/j.jss.2015.03.028. Epub 2015 Mar 18.

DOI:10.1016/j.jss.2015.03.028
PMID:25930169
Abstract

BACKGROUND

Postoperative pulmonary complications (PPCs) after major abdominal surgery are common and associated with significant morbidity and high cost of care. The objective of this study was to identify the risk factors for PPCs after major abdominal surgery.

MATERIALS AND METHODS

The American College of Surgeons' National Surgical Quality Improvement Program database from 2005-2012 was queried for patients who underwent major abdominal surgery (esophagectomy, gastrectomy, pacnreatectomy, enterectomy, hepatectomy, colectomy, and proctectomy). Predictors of PPCs were identified using multivariate logistic regression.

RESULTS

Of 165,196 patients who underwent major abdominal surgery 9595 (5.8%) suffered PPCs (pneumonia 3.2%, prolonged ventilator support ≥48 h 3.0%, and unplanned intubation 2.8%). On multivariate analysis, significant predictors of overall and individual PPCs include esophagectomy, advanced American Society of Anesthesiology Classification System, dependent functional status, prolonged operative time, age ≥80 y, severe chronic obstructive pulmonary disease, preoperative shock, ascites, and smoking. Obesity was not a risk factor. Female gender was overall protective for PPCs.

CONCLUSIONS

PPCs after abdominal procedures are associated with a number of clinical variables. Esophageal operations and American Society of Anesthesiology Classification System were the strongest predictors. These results provide a framework for identifying patients at risk for developing pulmonary complications after major abdominal surgery.

摘要

背景

腹部大手术后的术后肺部并发症(PPCs)很常见,且与显著的发病率和高昂的护理成本相关。本研究的目的是确定腹部大手术后PPCs的危险因素。

材料与方法

查询美国外科医师学会国家外科质量改进计划数据库中2005年至2012年接受腹部大手术(食管切除术、胃切除术、胰腺切除术、肠切除术、肝切除术、结肠切除术和直肠切除术)的患者。使用多因素逻辑回归确定PPCs的预测因素。

结果

在165196例接受腹部大手术的患者中,9595例(5.8%)发生了PPCs(肺炎3.2%,机械通气支持时间延长≥48小时3.0%,非计划插管2.8%)。多因素分析显示,总体和个体PPCs的显著预测因素包括食管切除术、美国麻醉医师协会分级系统高级别、依赖性功能状态、手术时间延长、年龄≥80岁、严重慢性阻塞性肺疾病、术前休克、腹水和吸烟。肥胖不是危险因素。女性总体上对PPCs有保护作用。

结论

腹部手术后的PPCs与许多临床变量相关。食管手术和美国麻醉医师协会分级系统是最强的预测因素。这些结果为识别腹部大手术后有发生肺部并发症风险的患者提供了一个框架。

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