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大脑后动脉假性动脉瘤——垂体瘤经蝶窦手术的一种罕见并发症:病例报告及文献综述

Posterior Cerebral Artery Pseudoaneurysm, a Rare Complication of Pituitary Tumor Transsphenoidal Surgery: Case Report and Literature Review.

作者信息

Lee Chih-Hsun, Chen Shu-Mei, Lui Tai-Ngar

机构信息

Department of Neurosurgery, Taipei Medical University - Wan-Fang Hospital, Taipei, Taiwan.

Department of Neurosurgery, Taipei Medical University - Wan-Fang Hospital, Taipei, Taiwan.

出版信息

World Neurosurg. 2015 Nov;84(5):1493.e1-3. doi: 10.1016/j.wneu.2015.04.043. Epub 2015 Apr 27.

Abstract

Endoscopic endonasal transsphenoidal surgery for pituitary tumors has been the standard therapy for decades. This approach offers surgeons an effective, safe, and wide exposure to the pituitary gland, with a relatively low mortality rate and acceptable complication rates. However, severe complications, including cerebrospinal fistula, meningitis, neural component injury, and vascular injury, may occur. One of the most common and severe complications is carotid artery injury; however, only 2 posterior cerebral artery injuries with pseudoaneurysm formation have been reported previously. One of them received bypass surgery and recovered well, but the other received endovascular treatment and died of intracranial hypertension. Herein, we report a rare case of iatrogenic pseudoaneurysm formation with hemorrhage after transsphenoidal surgery, in which tumor traction-related adjacent vessel injury was most likely. Aneurysm clipping, vascular bypass, and embolization are considered reasonable choices depending on the patient's condition for iatrogenic aneurysm formation. In our case, no surgical or endovascular intervention was performed, and the aneurysm healed spontaneously 3 weeks later.

摘要

几十年来,经鼻内镜经蝶窦手术一直是垂体肿瘤的标准治疗方法。这种方法为外科医生提供了一种有效、安全且能广泛暴露垂体的途径,死亡率相对较低,并发症发生率也可接受。然而,可能会出现严重并发症,包括脑脊液瘘、脑膜炎、神经成分损伤和血管损伤。最常见且严重的并发症之一是颈动脉损伤;然而,此前仅报道过2例伴有假性动脉瘤形成的大脑后动脉损伤。其中1例接受了搭桥手术,恢复良好,但另1例接受了血管内治疗,死于颅内高压。在此,我们报告1例经蝶窦手术后发生医源性假性动脉瘤形成并出血的罕见病例,其中肿瘤牵拉相关的相邻血管损伤很可能是原因。根据医源性动脉瘤形成的患者情况,动脉瘤夹闭、血管搭桥和栓塞被认为是合理的选择。在我们的病例中,未进行手术或血管内干预,动脉瘤在3周后自行愈合。

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