A novel HLA-A allele, HLA-A*02:544.
作者信息
Zhu X, Yang T, Tan R, Su P, Luo Z, Zhen X
机构信息
Department of Obstetrics and Gynecology, Peking University, Third Hospital, Beijing, PR China.
出版信息
Tissue Antigens. 2015 Jun;85(6):501-2. doi: 10.1111/tan.12560.
PMID:25940820
Abstract
The novel allele HLA-A02:544 has two nucleotide changes from its most closely related allele, HLA-A02:148. Firstly at nucleotide 255 where C → T (codon 60 GAC → GAT), resulting in a non-coding change as GAC and GAT both code for the same amino acid aspartic acid. Secondly at nucleotide 368 where T → G (codon 98 TTT → TGT) resulting in a coding change, 98 phenylalanine is changed to cysteine.
摘要
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