Anderson Joshua T, Haas Arnold R, Percy Rick, Woods Stephen T, Ahn Uri M, Ahn Nicholas U
*University Hospitals Case Medical Center Department of Orthopaedics, Case Western Reserve University School of Medicine, Cleveland, OH †Ohio Bureau of Workers' Compensation, Columbus, OH ‡New Hampshire NeuroSpine Institute, Bedford, NH; and §University Hospitals Case Medical Center Department of Orthopaedics, Cleveland, OH.
Spine (Phila Pa 1976). 2015 May 15;40(10):748-56. doi: 10.1097/BRS.0000000000000863.
Retrospective cohort study.
Determine how psychosocial factors, particularly depression, impact lumbar fusion outcomes in a workers' compensation (WC) setting.
WC patients are less likely to return to work (RTW) after fusion. Few studies evaluate risk factors within this clinically distinct population.
A total of 2799 Ohio WC subjects were identified who underwent lumbar fusion between 1993 and 2013 using Current Procedural Terminology (CPT) procedural and International Classification of Diseases, Ninth Revision (ICD-9) diagnosis codes. A total of 123 subjects were diagnosed with depression before fusion. Subjects with a smoking history, prior lumbar surgery, permanent disability, and failed back syndrome were excluded. The primary outcome was whether subjects returned to work within 2 years of fusion and sustained this RTW for more than 6 months of the following year. To determine the impact depression had on RTW status, we performed a multivariate logistic regression analysis. We also compared time absent from work and other secondary outcomes using χ2 and t tests.
Subjects with preoperative depression had significantly higher rates of legal representation, degenerative lumbar disease, and higher medical costs, and used opioid analgesics for considerably longer before and after fusion (P<0.001).Depression group (10.6% [13/123]) and controls (33.0% [884/2676]) met our RTW criteria (P<0.001). Preoperative depression was a negative predictor of RTW status (P<0.001; odds ratio [OR]: 0.38). Additional predictors included working during same week as fusion (OR: 2.15), age more than 50 years (OR: 0.58), chronic preoperative opioid analgesia (OR: 0.58), and legal representation (OR: 0.64). After surgery, depression subjects were absent from work 184 more days compared with controls (P<0.001).
Overall, RTW rates after fusion were low, which was especially true for those with pre-existing depression. Depression was a strong negative predictor of postoperative RTW status. Psychological screening and treatment may be beneficial in these subjects. The poor outcomes in this study may highlight a more limited role for fusion among WC subjects with chronic low back pain where RTW is the treatment goal.
回顾性队列研究。
确定心理社会因素,尤其是抑郁症,如何影响工伤赔偿(WC)环境下腰椎融合术的结果。
WC患者融合术后重返工作岗位(RTW)的可能性较小。很少有研究评估这一临床特征明显的人群中的风险因素。
利用当前操作术语(CPT)程序编码和国际疾病分类第九版(ICD-9)诊断编码,确定了1993年至2013年间在俄亥俄州接受腰椎融合术的2799名WC受试者。共有123名受试者在融合术前被诊断为抑郁症。排除有吸烟史、既往腰椎手术史、永久性残疾和腰椎管狭窄症的受试者。主要结局是受试者在融合术后2年内是否重返工作岗位,并在次年持续这种RTW状态超过6个月。为了确定抑郁症对RTW状态的影响,我们进行了多因素逻辑回归分析。我们还使用χ2检验和t检验比较了缺勤时间和其他次要结局。
术前患有抑郁症的受试者的法律代理率、退行性腰椎疾病发生率和医疗费用显著更高,并且在融合术前和术后使用阿片类镇痛药的时间长得多(P<0.001)。抑郁症组(10.6%[13/123])和对照组(33.0%[884/2676])达到了我们的RTW标准(P<)。术前抑郁症是RTW状态的负性预测因素(P=;优势比[OR]:0.38)。其他预测因素包括在融合术当周工作(OR:2.15)、年龄超过50岁(OR:0.58)、术前长期使用阿片类镇痛药(OR:0.58)和法律代理(OR:0.64)。术后,抑郁症受试者比对照组缺勤时间多184天(P<0.001)。
总体而言,融合术后的RTW率较低,对于那些既往患有抑郁症的患者尤其如此。抑郁症是术后RTW状态的强有力负性预测因素。心理筛查和治疗可能对这些受试者有益。本研究中的不良结局可能凸显了在以RTW为治疗目标的慢性下腰痛WC受试者中,融合术的作用更为有限。
3级。