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临床抑郁症是工伤赔偿对象腰椎融合术预后不良的有力预测指标。

Clinical depression is a strong predictor of poor lumbar fusion outcomes among workers' compensation subjects.

作者信息

Anderson Joshua T, Haas Arnold R, Percy Rick, Woods Stephen T, Ahn Uri M, Ahn Nicholas U

机构信息

*University Hospitals Case Medical Center Department of Orthopaedics, Case Western Reserve University School of Medicine, Cleveland, OH †Ohio Bureau of Workers' Compensation, Columbus, OH ‡New Hampshire NeuroSpine Institute, Bedford, NH; and §University Hospitals Case Medical Center Department of Orthopaedics, Cleveland, OH.

出版信息

Spine (Phila Pa 1976). 2015 May 15;40(10):748-56. doi: 10.1097/BRS.0000000000000863.

Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVE

Determine how psychosocial factors, particularly depression, impact lumbar fusion outcomes in a workers' compensation (WC) setting.

SUMMARY OF BACKGROUND DATA

WC patients are less likely to return to work (RTW) after fusion. Few studies evaluate risk factors within this clinically distinct population.

METHODS

A total of 2799 Ohio WC subjects were identified who underwent lumbar fusion between 1993 and 2013 using Current Procedural Terminology (CPT) procedural and International Classification of Diseases, Ninth Revision (ICD-9) diagnosis codes. A total of 123 subjects were diagnosed with depression before fusion. Subjects with a smoking history, prior lumbar surgery, permanent disability, and failed back syndrome were excluded. The primary outcome was whether subjects returned to work within 2 years of fusion and sustained this RTW for more than 6 months of the following year. To determine the impact depression had on RTW status, we performed a multivariate logistic regression analysis. We also compared time absent from work and other secondary outcomes using χ2 and t tests.

RESULTS

Subjects with preoperative depression had significantly higher rates of legal representation, degenerative lumbar disease, and higher medical costs, and used opioid analgesics for considerably longer before and after fusion (P<0.001).Depression group (10.6% [13/123]) and controls (33.0% [884/2676]) met our RTW criteria (P<0.001). Preoperative depression was a negative predictor of RTW status (P<0.001; odds ratio [OR]: 0.38). Additional predictors included working during same week as fusion (OR: 2.15), age more than 50 years (OR: 0.58), chronic preoperative opioid analgesia (OR: 0.58), and legal representation (OR: 0.64). After surgery, depression subjects were absent from work 184 more days compared with controls (P<0.001).

CONCLUSION

Overall, RTW rates after fusion were low, which was especially true for those with pre-existing depression. Depression was a strong negative predictor of postoperative RTW status. Psychological screening and treatment may be beneficial in these subjects. The poor outcomes in this study may highlight a more limited role for fusion among WC subjects with chronic low back pain where RTW is the treatment goal.

LEVEL OF EVIDENCE

摘要

研究设计

回顾性队列研究。

目的

确定心理社会因素,尤其是抑郁症,如何影响工伤赔偿(WC)环境下腰椎融合术的结果。

背景数据总结

WC患者融合术后重返工作岗位(RTW)的可能性较小。很少有研究评估这一临床特征明显的人群中的风险因素。

方法

利用当前操作术语(CPT)程序编码和国际疾病分类第九版(ICD-9)诊断编码,确定了1993年至2013年间在俄亥俄州接受腰椎融合术的2799名WC受试者。共有123名受试者在融合术前被诊断为抑郁症。排除有吸烟史、既往腰椎手术史、永久性残疾和腰椎管狭窄症的受试者。主要结局是受试者在融合术后2年内是否重返工作岗位,并在次年持续这种RTW状态超过6个月。为了确定抑郁症对RTW状态的影响,我们进行了多因素逻辑回归分析。我们还使用χ2检验和t检验比较了缺勤时间和其他次要结局。

结果

术前患有抑郁症的受试者的法律代理率、退行性腰椎疾病发生率和医疗费用显著更高,并且在融合术前和术后使用阿片类镇痛药的时间长得多(P<0.001)。抑郁症组(10.6%[13/123])和对照组(33.0%[884/2676])达到了我们的RTW标准(P<)。术前抑郁症是RTW状态的负性预测因素(P=;优势比[OR]:0.38)。其他预测因素包括在融合术当周工作(OR:2.15)、年龄超过50岁(OR:0.58)、术前长期使用阿片类镇痛药(OR:0.58)和法律代理(OR:0.64)。术后,抑郁症受试者比对照组缺勤时间多184天(P<0.001)。

结论

总体而言,融合术后的RTW率较低,对于那些既往患有抑郁症的患者尤其如此。抑郁症是术后RTW状态的强有力负性预测因素。心理筛查和治疗可能对这些受试者有益。本研究中的不良结局可能凸显了在以RTW为治疗目标的慢性下腰痛WC受试者中,融合术的作用更为有限。

证据级别

3级。

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