Lou Jing, Gong Wu-Xian, Wang Guang-Bin
Shandong Jinan Municipal Hospital of Traditional Chinese Medicine, Jinan 250012, PR China.
Shandong Medical Imaging Research Institute, Shandong University, Jinan 250021, PR China.
Int J Pediatr Otorhinolaryngol. 2015 Jul;79(7):1077-80. doi: 10.1016/j.ijporl.2015.04.033. Epub 2015 Apr 29.
The aim of this study was to determine differences in diameter of cochlear nerves (CN) among three measurement points at the midpoint of the internal auditory canal (IAC), IAC fundus and cochlear aperture, and to evaluate whether nerve size varies with age.
A total of 336 normal-hearing ears of 201 children were assessed, who were underwent 3D-Fiesta sequence scanning of inner ear. All subjects were divided into 12 groups at one year interval. The diameter measurements of CN were obtained in the midpoint of the IAC, IAC fundus and cochlear aperture respectively on the axial and oblique sagittal images of 3.0-T MRI. SPSS 18.0 statistics software was applied for data analysis, and all of the data showed a normal distribution and expressed in x ± s.
The diameters of normal-hearing children's CN at the midpoint of the IAC, IAC fundus and cochlear aperture were respectively: 1.12 ± 0.08 mm, 1.05 ± 0.06 mm, 0.87 ± 0.14 mm, and there were significant differences among the three measuring points (F = 527.57, p < 0.05). The diameters of the CN had no significant difference (p > 0.05) in age groups, gender and sides (p > 0.05), and there was no correlation between the diameters of normal children's CN and age (r is -0.129, 0.128 and -0.113, respectively).
The diameters of normal-hearing children's CN change with different points of the internal auditory canal, of which the maximum value is in the midpoint of the IAC, followed by the IAC fundus, and the cochlear aperture is at the minimum; moreover the normal size doesn't change with age.
本研究旨在确定内耳道中点、内耳道底部和蜗孔三个测量点处蜗神经（CN）直径的差异，并评估神经大小是否随年龄变化。
对201名儿童的336只听力正常的耳朵进行评估，这些儿童均接受了内耳的三维快速扰相稳态进动序列扫描。所有受试者按一岁间隔分为12组。在3.0-T磁共振成像的轴位和斜矢状位图像上，分别在内耳道中点、内耳道底部和蜗孔处测量CN的直径。应用SPSS 18.0统计软件进行数据分析，所有数据均呈正态分布，以x±s表示。
听力正常儿童在内耳道中点、内耳道底部和蜗孔处的CN直径分别为：1.12±0.08mm、1.05±0.06mm、0.87±0.14mm，三个测量点之间存在显著差异（F = 527.57，p < 0.05）。CN直径在年龄组、性别和侧别方面均无显著差异（p > 0.05），正常儿童CN直径与年龄之间也无相关性（r分别为-0.129、0.128和-0.113）。
听力正常儿童的CN直径在内耳道不同部位有所变化，其中最大值在内耳道中点，其次是内耳道底部，蜗孔处最小；而且正常大小不随年龄变化。
