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中间葡萄膜炎:免疫功能正常患者巨细胞病毒眼内感染的一种不寻常表现。

Intermediate uveitis: an unusual presentation of cytomegalovirus intraocular infection in an immunocompetent patient.

作者信息

Amin Rowayda M, Ostheimer Trucian, Butler Nicholas J

机构信息

The Wilmer Eye Institute, Division of Ocular Immunology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, Alexandria Faculty of Medicine, Ophthalmology department, Vitreoretinal diseases and Uveitis division, Alexandria, Egypt.

The Wilmer Eye Institute, Division of Ocular Immunology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

BMJ Case Rep. 2015 May 12;2015:bcr2014208521. doi: 10.1136/bcr-2014-208521.

Abstract

We report a case of cytomegalovirus (CMV) intraocular infection in an otherwise healthy 51-year-old patient, presenting atypically as isolated intermediate uveitis without retinitis or retinal vasculitis. The patient had a confirmed CMV infection as a cause of her intraocular inflammation via PCR DNA testing of an aqueous sample. Appropriate oral antiviral therapy was initiated, and resulted in complete resolution of inflammation and improvement in visual acuity. Prophylactic therapy was instituted thereafter.

摘要

我们报告一例51岁健康患者发生巨细胞病毒(CMV)眼内感染的病例,该病例表现不典型,仅为单纯性中间葡萄膜炎,无视网膜炎或视网膜血管炎。通过对房水样本进行PCR DNA检测,确诊该患者的CMV感染是其眼内炎症的病因。开始给予适当的口服抗病毒治疗,炎症完全消退,视力得到改善。此后进行了预防性治疗。

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本文引用的文献

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Cytomegalovirus anterior uveitis: outcome of treatment.巨细胞病毒性前葡萄膜炎:治疗结果。
Br J Ophthalmol. 2010 Dec;94(12):1648-52. doi: 10.1136/bjo.2009.167767. Epub 2010 Jun 24.

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