认知增强的传递与疗效评估方法。

Methods for delivering and evaluating the efficacy of cognitive enhancement.

作者信息

Harvey Philip D, Keefe Richard S E

机构信息

University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1450, Miami, FL, 33136, USA,

出版信息

Handb Exp Pharmacol. 2015;228:5-25. doi: 10.1007/978-3-319-16522-6_1.

DOI:10.1007/978-3-319-16522-6_1

PMID:25977078

Abstract

Cognitive deficits are related to impaired everyday functioning in multiple conditions and in healthy individuals. Treatment of cognitive functioning can be facilitated through either pharmacological or remediation strategies. The critical goals of cognitive enhancement are to improve everyday functioning in multiple domains. This chapter describes the strategies that are most desirable for the treatment of cognitive impairments and detection of potential benefits of treatment in cognitive and functional domains. These strategies include the use of performance-based assessments of cognition and functioning and the appropriate use of observational strategies to detect changes. Finally, we define several outcome-related goals and discuss the practicality of their measurement.

摘要

认知缺陷与多种疾病及健康个体的日常功能受损有关。认知功能的治疗可通过药物或康复策略来促进。认知增强的关键目标是改善多个领域的日常功能。本章描述了治疗认知障碍以及检测认知和功能领域治疗潜在益处最理想的策略。这些策略包括使用基于表现的认知和功能评估，以及适当地运用观察策略来检测变化。最后，我们定义了几个与结果相关的目标，并讨论了其测量的实用性。