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Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
Tetrahedron Lett. 2015 May 20;56(21):2832-2835. doi: 10.1016/j.tetlet.2015.04.061.
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Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
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Exploring the Activity Profile of TbrPDEB1 and hPDE4 Inhibitors Using Free Energy Perturbation.
ACS Med Chem Lett. 2022 May 23;13(6):904-910. doi: 10.1021/acsmedchemlett.1c00690. eCollection 2022 Jun 9.
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Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2).
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Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors.
Bioorg Med Chem. 2019 Sep 15;27(18):3998-4012. doi: 10.1016/j.bmc.2019.06.027. Epub 2019 Jun 18.

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Synthesis of new Spiropyrazole derivatives under microwaves irradiation and docking study for inhibition the microbes and COVID-19.
J Mol Struct. 2022 Dec 5;1269:133581. doi: 10.1016/j.molstruc.2022.133581. Epub 2022 Jun 25.
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Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect.
Eur J Med Chem. 2020 Jan 15;186:111893. doi: 10.1016/j.ejmech.2019.111893. Epub 2019 Nov 16.
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The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!
Front Pharmacol. 2015 Sep 7;6:185. doi: 10.3389/fphar.2015.00185. eCollection 2015.

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2
Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).
Bioorg Med Chem Lett. 2013 Nov 1;23(21):5971-4. doi: 10.1016/j.bmcl.2013.08.057. Epub 2013 Aug 21.
3
A current analysis of chemotherapy strategies for the treatment of human African trypanosomiasis.
Pathog Glob Health. 2013 Jul;107(5):242-52. doi: 10.1179/2047773213Y.0000000105.
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Pharmacological validation of Trypanosoma brucei phosphodiesterases as novel drug targets.
J Infect Dis. 2012 Jul 15;206(2):229-37. doi: 10.1093/infdis/jir857. Epub 2012 Jan 30.
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Target repurposing for neglected diseases.
Future Med Chem. 2011 Aug;3(10):1307-15. doi: 10.4155/fmc.11.92.
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Novel potent and selective σ ligands: evaluation of their agonist and antagonist properties.
J Med Chem. 2011 May 26;54(10):3669-73. doi: 10.1021/jm200144j. Epub 2011 Apr 21.

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