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伙伴关系对乌干达农村地区接受抗逆转录病毒治疗的感染艾滋病毒妇女使用避孕措施的影响。

The influence of partnership on contraceptive use among HIV-infected women accessing antiretroviral therapy in rural Uganda.

作者信息

Nieves Christina I, Kaida Angela, Seage George R, Kabakyenga Jerome, Muyindike Winnie, Boum Yap, Mocello A Rain, Martin Jeffrey N, Hunt Peter W, Haberer Jessica E, Bangsberg David R, Matthews Lynn T

机构信息

Harvard School of Public Health, Boston, United States.

Simon Fraser University, Faculty of Health Sciences, Burnaby, Canada.

出版信息

Contraception. 2015 Aug;92(2):152-9. doi: 10.1016/j.contraception.2015.04.011. Epub 2015 May 14.

Abstract

OBJECTIVE

The objective was to determine individual and dyadic factors associated with effective contraceptive use among human immunodeficiency virus (HIV)-infected women accessing antiretroviral therapy (ART) in rural Uganda.

STUDY DESIGN

HIV-infected women enrolled in the Uganda AIDS Rural Treatment Outcomes cohort completed questionnaires (detailing sociobehavioral characteristics, sexual and reproductive history, contraceptive use, fertility desires) and phlebotomy (October 2011-March 2013). We describe prevalence of effective contraceptive use (i.e., consistent condom use and/or oral contraceptives, injectable hormonal contraception, intrauterine device, female sterilization) in the previous 6 months among sexually active, nonpregnant women (18-40 years). We assessed covariates of contraceptive use using multivariable logistic regression.

RESULTS

A total of 362 women (median values: age 30 years, CD4 count 397 cells/mm(3), 4.0 years since ART initiation) were included. Among 284 sexually active women, 50% did not desire a(nother) child, and 51% had a seroconcordant partner. Forty-five percent (n=127) reported effective contraceptive use, of whom 57% (n=72) used condoms, 42% (n=53) injectables, 12% (n=15) oral contraceptives and 11% (n=14) other effective methods. Dual contraception was reported by 6% (n=8). Only "partnership fertility desire" was independently associated with contraceptive use; women who reported that neither partner desired a child had significantly increased odds of contraceptive use (adjusted odds ratio: 2.40, 95% confidence interval: 1.07-5.35) compared with women in partnerships where at least one partner desired a child.

CONCLUSIONS

Less than half of sexually active HIV-infected women accessing ART used effective contraception, of which 44% (n=56) relied exclusively on male condoms, highlighting a continued need to expand access to a wider range of longer-acting female-controlled contraceptive methods. Association with partnership fertility desire underscores the need to include men in reproductive health programming.

IMPLICATIONS STATEMENT

Less than half of sexually active HIV-infected women accessing ART in rural Uganda reported using effective contraception, of whom 44% relied exclusively on the male condom. These findings highlight the need to expand access to a wider range of longer-acting, female-controlled contraceptive methods for women seeking to limit or space pregnancies. Use of contraception was more likely when both the male and female partner expressed concordant desires to limit future fertility, emphasizing the importance of engaging men in reproductive health programming.

摘要

目的

确定乌干达农村地区接受抗逆转录病毒治疗(ART)的感染人类免疫缺陷病毒(HIV)的女性中与有效避孕使用相关的个体和二元因素。

研究设计

纳入乌干达艾滋病农村治疗结果队列中的感染HIV的女性,她们于2011年10月至2013年3月期间完成了问卷调查(详细描述社会行为特征、性与生殖史、避孕使用情况、生育意愿)并接受了静脉采血。我们描述了性活跃、未怀孕的18至40岁女性在过去6个月中有效避孕使用(即持续使用避孕套和/或口服避孕药、注射用激素避孕、宫内节育器、女性绝育)的情况。我们使用多变量逻辑回归评估避孕使用的协变量。

结果

共纳入362名女性(中位数:年龄30岁,CD4细胞计数397个/mm³,开始接受ART治疗4.0年)。在284名性活跃女性中,50%不想要(另)一个孩子,51%有血清学一致的伴侣。45%(n = 127)报告使用了有效避孕措施,其中57%(n = 72)使用避孕套,42%(n = 53)使用注射剂,12%(n = 15)使用口服避孕药,11%(n = 14)使用其他有效方法。6%(n = 8)报告使用了双重避孕措施。只有“伴侣生育意愿”与避孕使用独立相关;与至少一方想要孩子的伴侣关系中的女性相比,报告双方都不想要孩子的女性避孕使用几率显著增加(调整后的优势比:2.40,95%置信区间:1.07 - 5.35)。

结论

接受ART治疗的性活跃感染HIV的女性中,不到一半使用了有效避孕措施,其中44%(n = 56)仅依赖男性避孕套,这突出表明仍需扩大提供更广泛的长效女性控制避孕方法。与伴侣生育意愿的关联强调了将男性纳入生殖健康规划的必要性。

启示声明

在乌干达农村地区,接受ART治疗的性活跃感染HIV的女性中,不到一半报告使用了有效避孕措施,其中44%仅依赖男性避孕套。这些发现突出表明,对于寻求限制或间隔怀孕的女性,需要扩大提供更广泛的长效、女性控制避孕方法。当男性和女性伴侣都表达了限制未来生育的一致意愿时,使用避孕措施的可能性更大,这强调了让男性参与生殖健康规划的重要性。

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