甲状旁腺干预对慢性肾脏病-矿物质和骨异常管理的临床意义。
Clinical significance of parathyroid intervention on CKD-MBD management.
作者信息
Ogata Hiroaki, Mizobuchi Masahide, Koiwa Fumihiko, Kinugasa Eriko, Akizawa Tadao
机构信息
Department of Internal Medicine , Showa University Northern Yokohama Hospital , Yokohama.
Division of Nephrology, Department of Internal Medicine , Showa University Fujigaoka Hospital , Yokohama , Japan.
出版信息
NDT Plus. 2008 Aug;1(Suppl 3):iii9-iii13. doi: 10.1093/ndtplus/sfn080.
Recently published 'Guidelines for the management of secondary hyperparathyroidism in chronic dialysis patients' by the Japanese Society for Dialysis Therapy advocate that percutaneous ethanol injection into enlarged glands, which has been considered as the only alternative to parathyroidectomy (PTx), should be indicated in patients with a single enlarged parathyroid gland (estimated volume >500 mm(3), or estimated major axis >10 mm), and that PTx should be recommended in patients with multiple enlarged glands. Cinacalcet cannot achieve optimal control of chronic kidney disease-mineral bone disorder in all patients, and parathyroid intervention will be required in a considerable number of patients with refractory secondary hyperparathyroidism.
日本透析治疗学会最近发布的《慢性透析患者继发性甲状旁腺功能亢进管理指南》主张，对于单个甲状旁腺肿大（估计体积>500立方毫米，或估计长轴>10毫米）的患者，应采用经皮乙醇注射至肿大腺体的方法，该方法一直被视为甲状旁腺切除术（PTx）的唯一替代方案；对于多个甲状旁腺肿大的患者，则应推荐进行PTx。西那卡塞无法使所有患者的慢性肾脏病-矿物质和骨异常得到最佳控制，相当一部分难治性继发性甲状旁腺功能亢进患者仍需要进行甲状旁腺干预。
Zotero 插件