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一种挖掘临床数据的方法:来自TRANSFoRm项目的经验。

A methodology for mining clinical data: experiences from TRANSFoRm project.

作者信息

Danger Roxana, Corrigan Derek, Soler Jean K, Kazienko Przemyslaw, Kajdanowicz Tomasz, Majeed Azeem, Curcin Vasa

机构信息

Imperial College London, London, UK.

Royal College of Surgeons in Ireland, Dublin, Ireland.

出版信息

Stud Health Technol Inform. 2015;210:85-9.

PMID:25991107
Abstract

Data mining of electronic health records (eHRs) allows us to identify patterns of patient data that characterize diseases and their progress and learn best practices for treatment and diagnosis. Clinical Prediction Rules (CPRs) are a form of clinical evidence that quantifies the contribution of different clinical data to a particular clinical outcome and help clinicians to decide the diagnosis, prognosis or therapeutic conduct for any given patient. The TRANSFoRm diagnostic support system (DSS) is based on the construction of an ontological repository of CPRs for diagnosis prediction in which clinical evidence is expressed using a unified vocabulary. This paper explains the proposed methodology for constructing this CPR repository, addressing algorithms and quality measures for filtering relevant rules. Some preliminary application results are also presented.

摘要

电子健康记录(eHRs)的数据挖掘使我们能够识别表征疾病及其进展的患者数据模式,并学习治疗和诊断的最佳实践。临床预测规则(CPRs)是一种临床证据形式,它量化了不同临床数据对特定临床结果的贡献,并帮助临床医生为任何给定患者决定诊断、预后或治疗行为。TRANSFoRm诊断支持系统(DSS)基于构建用于诊断预测的CPRs本体知识库,其中临床证据使用统一词汇表来表达。本文解释了构建此CPR知识库的提议方法,讨论了用于筛选相关规则的算法和质量度量。还展示了一些初步应用结果。

相似文献

1
A methodology for mining clinical data: experiences from TRANSFoRm project.一种挖掘临床数据的方法:来自TRANSFoRm项目的经验。
Stud Health Technol Inform. 2015;210:85-9.
2
A Decision Fusion Framework for Treatment Recommendation Systems.一种用于治疗推荐系统的决策融合框架。
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Identifying Patients with Depression Using Free-text Clinical Documents.使用自由文本临床文档识别抑郁症患者。
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Using EHRs for Heart Failure Therapy Recommendation Using Multidimensional Patient Similarity Analytics.利用多维患者相似性分析,通过电子健康记录进行心力衰竭治疗推荐。
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Functionality of Triggers for Epilepsy Patients Assessed by Text and Data Mining of Medical and Nursing Records.通过医疗和护理记录的文本及数据挖掘评估癫痫患者触发器的功能。
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引用本文的文献

1
Clinical Decision Support and Natural Language Processing in Medicine: Systematic Literature Review.临床决策支持与医学自然语言处理:系统文献回顾。
J Med Internet Res. 2024 Sep 30;26:e55315. doi: 10.2196/55315.
2
Requirements and validation of a prototype learning health system for clinical diagnosis.临床诊断原型学习健康系统的要求与验证
Learn Health Syst. 2017 May 31;1(4):e10026. doi: 10.1002/lrh2.10026. eCollection 2017 Oct.
3
An Alternative Paradigm for Evidence-Based Medicine: Revisiting Lawrence Weed, MD's Systems Approach.
循证医学的另一种范式:重温劳伦斯·威德医学博士的系统方法。
Perm J. 2017;21:16-147. doi: 10.7812/TPP/16-147.
4
A Multistep Maturity Model for the Implementation of Electronic and Computable Diagnostic Clinical Prediction Rules (eCPRs).电子和可计算诊断临床预测规则(eCPRs)实施的多步骤成熟度模型
EGEMS (Wash DC). 2015 Jul 7;3(2):1153. doi: 10.13063/2327-9214.1153. eCollection 2015.