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[嗜酸性食管炎的诊断特征]

[Eosinophilic esophagitis diagnostic features].

出版信息

Eksp Klin Gastroenterol. 2015(2):52-9.

Abstract

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by eosinophilic infiltration and inflammation of the gastrointestinal tract in the absence of other causes of tissue eosinophilia. The clinical course of EoE like gastroesophageal reflux disease with eosinophilic infiltration of the esophageal epithelium. EoE widely diagnosed abroad in children and adults, whereas in Russia the disease is almost never diagnosed. Upon detection of eosinophilia in the biopsy of the esophagus should exclude other causes. The correct clinical diagnosis in combination with the study of biopsy tissue of the esophagus and other laboratory methods (including allergic testing) is crucial in achieving the effectiveness of therapy EoE.

摘要

嗜酸性食管炎(EoE)是一种慢性炎症性疾病,其特征为胃肠道嗜酸性粒细胞浸润和炎症,且不存在其他导致组织嗜酸性粒细胞增多的原因。EoE的临床病程类似于伴有食管上皮嗜酸性粒细胞浸润的胃食管反流病。EoE在国外被广泛诊断于儿童和成人,而在俄罗斯这种疾病几乎从未被诊断出来。在食管活检中检测到嗜酸性粒细胞增多时,应排除其他病因。正确的临床诊断结合食管活检组织研究及其他实验室方法(包括过敏检测)对于实现EoE治疗的有效性至关重要。

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