Lloyd Amanda A, Graves Michael S, Ross Edward V
Scripps Clinic, La Jolla, California, 92037.
Lasers Surg Med. 2015 Jul;47(5):386-7. doi: 10.1002/lsm.22353. Epub 2015 May 20.
Cutaneous siderosis is accumulation of iron in the dermis and the subcutaneous tissue secondary to extravasation of an intramuscular or intravascular iron injection. It presents as varying shades of brown macules with no distinct contours. The hyperpigmentation is permanent without treatment.
Q-switched lasers have been used effectively to treat lentigines and tattoos however, there is little data on the treatment of cutaneous siderosis with lasers. Our objective was to effectively treat cutaneous siderosis with a Q-switched alexandrite laser.
A 50-year-old female had received nine injections of intramuscular iron dextran, one injection every 2 weeks alternating right buttock and left buttock over the course of 5 months. A couple of weeks after her 9th injection which was on the left, she noted brown hyperpigmentation in the injection area with the left worse than the right. She waited 3 months for the hyperpigmentation to self-resolve before presenting in our clinic. We utilized the Q-switched alexandrite laser to treat the patient with a test spot. One week later, there was nice partial clearance from the test spot so we commenced full treatment of the hyperpigmentation. There was significant improvement after the first treatment and she has been treated 4 times with continued improvement over the past 2 months.
The Q-switched alexandrite laser is a useful tool in the treatment of cutaneous siderosis secondary to iron injection.
皮肤铁质沉着症是由于肌肉内或血管内铁注射外渗,导致铁在真皮和皮下组织中蓄积。其表现为棕色斑,颜色深浅不一,边界不清晰。未经治疗,色素沉着会持续存在。
调Q激光已有效用于治疗雀斑和纹身,然而,关于激光治疗皮肤铁质沉着症的数据较少。我们的目的是用调Q紫翠宝石激光有效治疗皮肤铁质沉着症。
一名50岁女性在5个月内每2周交替在右臀部和左臀部注射一次右旋糖酐铁,共注射了9次。在第9次(左侧)注射几周后,她注意到注射部位出现棕色色素沉着,左侧比右侧更严重。她等待3个月,希望色素沉着自行消退,之后前来我们诊所就诊。我们用调Q紫翠宝石激光对患者进行了试验光斑治疗。一周后,试验光斑有明显的部分清除效果,于是我们开始对色素沉着进行全面治疗。首次治疗后有显著改善,在过去2个月里她接受了4次治疗,病情持续好转。
调Q紫翠宝石激光是治疗铁注射所致皮肤铁质沉着症的有效工具。