Hashimoto Makoto, Fukui Toshihiro, Takanashi Shuichiro
Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.
Ann Thorac Cardiovasc Surg. 2015;21(5):452-8. doi: 10.5761/atcs.oa.14-00305. Epub 2015 May 25.
The feasibility of using bilateral internal thoracic artery (BITA) grafts for coronary artery bypass grafting (CABG) in octogenarians is not clear. This study aimed to compare outcomes between use of BITA and single internal thoracic artery (SITA) grafts in octogenarians undergoing isolated CABG.
Isolated CABG was performed in 1,566 patients at the Sakakibara Heart Institute between September 2004 and December 2012. Of these, 125 consecutive octogenarians were included and divided into two groups, according to the use of BITA grafts (101 subjects) or SITA grafts (24 subjects). Early and late outcomes were compared between groups.
The preoperative patient characteristics were similar between the two groups. Early outcomes were similar, including hospital death or deep sternal infection. The estimated 5-year survival rate was similar in the BITA and SITA groups (78% vs 62%, p = 0.269). Freedom from major adverse cardiac or cerebrovascular events was significantly higher in the BITA group than in the SITA group after 5 years (90% vs 75%, p = 0.032).
Our results suggest that use of BITA grafts for CABG is feasible and beneficial in octogenarians, resulting in improved late outcomes without increased operative risk.
在八旬老人中使用双侧胸廓内动脉(BITA)进行冠状动脉旁路移植术(CABG)的可行性尚不清楚。本研究旨在比较在接受单纯CABG的八旬老人中使用BITA和单支胸廓内动脉(SITA)进行移植的效果。
2004年9月至2012年12月期间,在酒匂心脏研究所对1566例患者进行了单纯CABG。其中,连续纳入125例八旬老人,根据是否使用BITA分为两组,使用BITA的101例和使用SITA的24例。比较两组的早期和晚期效果。
两组患者术前特征相似。早期效果相似,包括住院死亡或深部胸骨感染。BITA组和SITA组的估计5年生存率相似(78%对62%,p = 0.269)。5年后,BITA组无重大不良心脏或脑血管事件的发生率显著高于SITA组(90%对75%,p = 0.032)。
我们的结果表明,在八旬老人中使用BITA进行CABG是可行且有益的,可改善晚期效果且不增加手术风险。