综述文章：用于治疗炎症性肠病的药物的药代动力学和药效学
Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment.
作者信息
Quetglas E G, Armuzzi A, Wigge S, Fiorino G, Barnscheid L, Froelich M, Danese Silvio
机构信息
Project Strategy & Science, Grünenthal GmbH, Aachen, Germany.
出版信息
Eur J Clin Pharmacol. 2015 Jul;71(7):773-99. doi: 10.1007/s00228-015-1862-7. Epub 2015 May 27.
PMID:26008212
Abstract
BACKGROUND
The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism.
RESULTS
It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics.
摘要
背景
以下综述汇编了关于治疗机体炎症性肠病最常用化合物行为的最新进展和知识。
结果
它考虑了每个实体的临床方面以及通过血浆监测、组织浓度和药物遗传学某些方面所支持的药代动力学/药效学关系。
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