Bužgová Radka, Jarošová Darja, Hajnová Erika
Department of Nursing and Midwifery, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava 700 30, Czech Republic.
Clinic of Oncology, University Hospital Ostrava, Czech Republic; Department of Nursing and Midwifery, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava 700 30, Czech Republic.
Eur J Oncol Nurs. 2015 Dec;19(6):667-72. doi: 10.1016/j.ejon.2015.04.006. Epub 2015 May 23.
The study aimed at assessing the presence of anxiety and depression in cancer inpatients receiving palliative care at an oncology department using the Hospital Anxiety and Depression Scale (HADS) and determining whether anxiety and depression contribute to a lower quality of life controlled for pain and illness severity.
This cross-sectional study comprised 225 advanced cancer inpatients (a mean age of 65.1 years). Data were collected with the HADS, EORTC QLQ-C30 and Karnofsky Performance Status scale.
Anxiety (HADS-a ≥8) was found in 33.9% and depression (HADS-d ≥8) in 47.6% of patients. Higher anxiety scores were observed in patients living with a partner (p = 0.042) and non-religious patients (p = 0.045). Correlations were found between anxiety, depression and all quality of life dimensions (r = 0.31-0.63). Multiple regression analysis showed that anxiety and depression contribute to lower physical and emotional functioning. Patients with anxiety (HADS-a ≥8) and depression (HADS-d ≥8) reported a lower total quality of life (p < 0.01).
Management of anxiety and depression in cancer patients receiving palliative care may contribute to improvement in certain quality of life dimensions.
本研究旨在使用医院焦虑抑郁量表（HADS）评估肿瘤科室接受姑息治疗的癌症住院患者中焦虑和抑郁的存在情况，并确定焦虑和抑郁是否会导致在控制疼痛和疾病严重程度的情况下生活质量降低。
这项横断面研究包括225名晚期癌症住院患者（平均年龄65.1岁）。使用HADS、欧洲癌症研究与治疗组织生活质量核心问卷（EORTC QLQ-C30）和卡诺夫斯基功能状态量表收集数据。
33.9%的患者存在焦虑（HADS-a≥8），47.6%的患者存在抑郁（HADS-d≥8）。与伴侣同住的患者（p = 0.042）和无宗教信仰的患者（p = 0.045）焦虑得分更高。焦虑、抑郁与所有生活质量维度之间均存在相关性（r = 0.31 - 0.63）。多元回归分析表明，焦虑和抑郁会导致身体和情感功能下降。焦虑（HADS-a≥8）和抑郁（HADS-d≥8）的患者报告的总体生活质量较低（p < 0.01）。
对接受姑息治疗的癌症患者的焦虑和抑郁进行管理可能有助于改善某些生活质量维度。
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